Chisholm Brock, Freeman Daniel, Cooke Anne
Department of Mental Health, St. George's, University of London, UK.
Br J Clin Psychol. 2006 Nov;45(Pt 4):545-59. doi: 10.1348/014466505X90136.
The experience of a psychotic episode can sometimes lead to post-traumatic stress disorder (PTSD) symptoms. The objective of the research was to identify candidate predictors of such negative reactions for future prospective study. We examined six predictors identified from the PTSD and psychosis literatures in a retrospective study: a history of previous trauma, a history of previous episodes of psychosis, perceived helplessness and uncontrollability at the time of the index psychotic episode, the content of persecutory delusions at episode and the perceived presence of crisis support after the psychotic episode.
The design was a cross-sectional self-report and interview study of people with recently remitted symptoms of psychosis.
36 individuals with delusions and hallucinations that had remitted in the past year were assessed for the presence of PTSD symptoms in reaction to their most recent psychotic episode. Measures of the potential predictors were also taken at this point and associations with PTSD symptoms tested.
61% of the individuals with remitted positive symptoms had a reaction to their psychotic episode that was potentially severe enough to receive a PTSD diagnosis. Higher levels of PTSD symptoms were associated with all six predictors tested.
The study provides further evidence that negative reactions to psychotic episodes are relatively common. Clinicians may wish to assess for such symptoms. The study extended these findings by identifying a number of candidate psychological predictors of PTSD reactions such as perceptions of uncontrollability and absence of support. Prospective longitudinal studies are required to test the causal significance of these factors. More broadly, the findings indicate that traumatic stress in response to intra-psychic events such as delusions can be understood in similar ways to traumatic stress arising from physical traumas such as disasters.
精神病发作的经历有时会导致创伤后应激障碍(PTSD)症状。本研究的目的是确定此类负面反应的候选预测因素,以供未来的前瞻性研究使用。我们在一项回顾性研究中考察了从PTSD和精神病相关文献中确定的六个预测因素:既往创伤史、既往精神病发作史、在首次精神病发作时感知到的无助感和不可控感、发作时迫害妄想的内容以及精神病发作后感知到的危机支持情况。
本设计为对近期精神病症状已缓解者的横断面自我报告和访谈研究。
对36名在过去一年中妄想和幻觉已缓解的个体进行评估,以确定其对最近一次精神病发作的反应中是否存在PTSD症状。此时还对潜在预测因素进行了测量,并测试了与PTSD症状的关联。
61%的阳性症状已缓解的个体对其精神病发作的反应可能严重到足以被诊断为PTSD。较高水平的PTSD症状与所有六个测试的预测因素相关。
该研究提供了进一步的证据,表明对精神病发作的负面反应相对常见。临床医生可能希望评估此类症状。该研究通过确定一些PTSD反应的候选心理预测因素,如不可控感和缺乏支持的感知,扩展了这些发现。需要进行前瞻性纵向研究来检验这些因素的因果意义。更广泛地说,研究结果表明,对诸如妄想等内心事件产生的创伤性应激可以用与对诸如灾难等身体创伤产生的创伤性应激类似的方式来理解。