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日本首例机器人辅助根治性前列腺切除术系列研究:既往腹部手术对手术结果的影响

Robot-assisted radical prostatectomy in an initial Japanese series: the impact of prior abdominal surgery on surgical outcomes.

作者信息

Yumioka Tetsuya, Iwamoto Hideto, Masago Toshihiko, Morizane Shuichi, Yao Akihisa, Honda Masashi, Muraoka Kuniyasu, Sejima Takehiro, Takenaka Atsushi

机构信息

Division of Urology, Department of Surgery, Tottori University Faculty of Medicine, Yonago, Tottori, Japan.

出版信息

Int J Urol. 2015 Mar;22(3):278-82. doi: 10.1111/iju.12678. Epub 2014 Nov 25.

Abstract

OBJECTIVES

To evaluate the influence of prior abdominal surgery on surgical outcomes of robot-assisted radical prostatectomy in an early single center experience in Japan.

METHODS

We reviewed medical records of patients with localized prostate cancer who underwent robot-assisted radical prostatectomy from October 2010 to September 2013 at Tottori University Faculty of Medicine, Yonago, Tottori, Japan. Patients with prior abdominal surgery were compared with those with no prior surgery with respect to total operative time, port-insertion time, console time, positive surgical margin and perioperative complication rate. Furthermore, the number of patients requiring minimal adhesion lysis was compared between the two groups.

RESULTS

Of 150 patients who underwent robot-assisted radical prostatectomy, 94 (63%) had no prior abdominal surgery, whereas 56 patients (37%) did. The mean total operative time was 329 and 333 min (P = 0.340), mean port insertion time was 40 and 34.5 min (P = 0.003), mean console time was 255 and 238 min (P = 0.145), a positive surgical margin was observed in 17.9% and 17.0% patients (P = 0.896), and the incidence of perioperative complications was 25% and 23.4% (P = 0.825), respectively, in those with and without prior abdominal surgery. In the prior abdominal surgery group, 48 patients (80.4%) required adhesion lysis at the time of trocar placement or while operating the robotic console.

CONCLUSION

Robot-assisted radical prostatectomy appears to be a safe approach for patients with prior abdominal surgery without increasing total operative time, robotic console time, positive surgical margin or the incidence of perioperative complications.

摘要

目的

在日本一家单中心的早期经验中,评估既往腹部手术对机器人辅助根治性前列腺切除术手术结果的影响。

方法

我们回顾了2010年10月至2013年9月在日本鸟取县米子市鸟取大学医学部接受机器人辅助根治性前列腺切除术的局限性前列腺癌患者的病历。将有既往腹部手术史的患者与无既往手术史的患者在总手术时间、端口插入时间、控制台操作时间、手术切缘阳性率和围手术期并发症发生率方面进行比较。此外,还比较了两组中需要进行最小限度粘连松解的患者数量。

结果

在150例行机器人辅助根治性前列腺切除术的患者中,94例(63%)无既往腹部手术史,而56例(37%)有。有既往腹部手术史患者的平均总手术时间为329分钟,无既往腹部手术史患者为333分钟(P = 0.340);平均端口插入时间分别为40分钟和34.5分钟(P = 0.003);平均控制台操作时间分别为255分钟和238分钟(P = 0.145);手术切缘阳性率在有既往腹部手术史患者中为17.9%,无既往腹部手术史患者中为17.0%(P = 0.896);围手术期并发症发生率分别为25%和23.4%(P = 0.825)。在既往腹部手术组中,48例(80.4%)患者在放置套管针时或操作机器人控制台时需要进行粘连松解。

结论

对于有既往腹部手术史的患者,机器人辅助根治性前列腺切除术似乎是一种安全的方法,不会增加总手术时间、机器人控制台操作时间、手术切缘阳性率或围手术期并发症的发生率。

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