Ki E Y, Park J S, Mun J B, Hur S Y
Eur J Gynaecol Oncol. 2014;35(5):584-8.
Malignant mixed mesodermal tumors (MMMTs) are highly aggressive and usually diagnosed at advanced stages. MMMT originates from either the ovary or the uterus. Because this disease is relatively rare, an optimal treatment modality has not yet been established. The authors report four cases of ovarian MMMT (one heterologous MMMT and three homologous MMMTs) during 1990-2011. The patients underwent operation immediately after histopathologically confirmation and were treated with platinum-based combination chemotherapy. The extent of operation, the outcomes of radiation therapy, and the proper chemotherapeutic regimen are still controversial. The authors report herein four cases of ovarian MMMTs alone with a brief literature review.
恶性混合性中胚层肿瘤（MMMTs）具有高度侵袭性，通常在晚期才被诊断出来。MMMT起源于卵巢或子宫。由于这种疾病相对罕见，尚未确立最佳的治疗方式。作者报告了1990年至2011年间4例卵巢MMMT（1例异源性MMMT和3例同源性MMMT）。患者在组织病理学确诊后立即接受手术，并接受了铂类联合化疗。手术范围、放射治疗效果以及合适的化疗方案仍存在争议。作者在此仅报告4例卵巢MMMT病例并进行简要文献综述。
