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[不同干燥方法对五味子果实质量的影响]

[Influlance of different drying methods on quality of Schisandrae Chinensis Fructus].

作者信息

An Kai-Long, Li De-Kun, Zhou Da-Zheng, Ye Zheng-Liang, Guo Qiao-Sheng

出版信息

Zhongguo Zhong Yao Za Zhi. 2014 Aug;39(15):2900-6.

Abstract

OBJECTIVE

To study the influence of different drying methods on the quality of Schisandrae Chinensis Fructus and thus provide useful reference for its proper drying methods.

METHOD

Schisandrae Chinensis Fructus was processed by eight drying methods including vacuum freeze drying, natural drying in the shade, drying in the sun, oven drying and vacuum drying under different temperature. The contents of the functional ingredients includes chisandrin, gomisin D, gomisin J, schisandrol B, angeloylgomisin H, angeloylgomisin Q, gomisin G, schisantherin A, deoxyschisandrin, schisandrin B, schisandrin C, 5-HMF, total aids and total sugars. The main components change after drying were analyzed by HPLC, ultraviolet spectrophotometry and potentiometric titration. Principal component analysis (PCA) was carried out by SPSS software to evaluate the quality of different processed products from Schisandrae Chinensis Fructus.

RESULT

All these results are in accordance with the requirements of Chinese Pharmacopoeia published in 2010, the contents of schisandrin and total eleven lignans were the highest using vacuum drying, and 5-HMF were the lower, oven drying made little difference but with lower schisandrin and higher 5-HMF as the heat increased.

CONCLUSION

Different drying methods have significant influence on the quality of Schisandrae Chinensis Fructus. Oven drying under 5°C should be adopted to substitute drying in the sun according to the China Pharmacopoeia published in 2010 for Schisandrae Chinensis Fructus by comprehensive analysis of the cost, content and practicality.

摘要

目的

研究不同干燥方法对五味子质量的影响,为其适宜干燥方法提供参考依据。

方法

采用真空冷冻干燥、自然阴干、晒干、烘干及不同温度真空干燥等8种干燥方法对五味子进行加工处理。测定其活性成分五味子醇甲、戈米辛D、戈米辛J、五味子醇乙、当归酰戈米辛H、当归酰戈米辛Q、戈米辛G、五味子酯甲、五味子甲素、五味子乙素、五味子丙素、5-羟甲基糠醛、总灰分及总糖的含量。采用高效液相色谱法、紫外分光光度法及电位滴定法分析干燥后主要成分的变化。运用SPSS软件进行主成分分析(PCA),评价不同加工方法所得五味子制品的质量。

结果

各项检测结果均符合2010年版《中国药典》要求,真空干燥法所得五味子醇甲及11种木脂素类成分含量最高,5-羟甲基糠醛含量较低;烘干法差异较小,但随着温度升高五味子醇甲含量降低,5-羟甲基糠醛含量升高。

结论

不同干燥方法对五味子质量有显著影响。综合成本、含量及实用性等因素,建议2010年版《中国药典》收载的五味子干燥方法由晒干改为5℃烘干。

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