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阿托品抑制疗法在英国斜视治疗实践中治疗弱视的应用。

Use of atropine penalization to treat amblyopia in UK orthoptic practice.

作者信息

Piano Marianne, O'Connor Anna R, Newsham David

出版信息

J Pediatr Ophthalmol Strabismus. 2014 Nov-Dec;51(6):363-9. doi: 10.3928/01913913-20141021-08.

Abstract

PURPOSE

To compare clinical practice patterns regarding atropine penalization use by UK orthoptists to the current evidence base and identify any existing barriers against use of AP as first-line treatment.

METHODS

An online survey was designed to assess current practice patterns of UK orthoptists using atropine penalization. They were asked to identify issues limiting their use of atropine penalization and give opinions on its effectiveness compared to occlusion. Descriptive statistics and content analysis were applied to the results.

RESULTS

Responses were obtained from 151 orthoptists throughout the United Kingdom. The main perceived barriers to use of atropine penalization were inability to prescribe atropine and supply difficulties. However, respondents also did not consider atropine penalization as effective as occlusion in treating amblyopia, contrary to recent research findings. Patient selection criteria and treatment administration largely follow current evidence. More orthoptists use atropine penalization as first-line treatment than previously reported.

CONCLUSIONS

Practitioners tend to closely follow the current evidence base when using atropine penalization, but reluctance in offering it as first-line treatment or providing a choice for parents between occlusion and atropine still remains. This may result from concerns regarding atropine's general efficacy, side effects, and risk of reverse amblyopia. Alternatively, as demonstrated in other areas of medicine, it may reflect the inherent delay of research findings translating to clinical practice changes.

摘要

目的

比较英国斜视矫正师使用阿托品压抑疗法的临床实践模式与当前的证据基础,并确定在将阿托品压抑疗法用作一线治疗方面存在的任何障碍。

方法

设计了一项在线调查,以评估英国斜视矫正师使用阿托品压抑疗法的当前实践模式。要求他们指出限制其使用阿托品压抑疗法的问题,并就其与遮盖疗法相比的有效性发表意见。对结果应用描述性统计和内容分析。

结果

收到了来自英国各地151名斜视矫正师的回复。使用阿托品压抑疗法的主要认知障碍是无法开具阿托品处方和供应困难。然而,与最近的研究结果相反,受访者也不认为阿托品压抑疗法在治疗弱视方面与遮盖疗法一样有效。患者选择标准和治疗管理在很大程度上遵循当前证据。与之前报道的相比,更多的斜视矫正师将阿托品压抑疗法用作一线治疗。

结论

从业者在使用阿托品压抑疗法时倾向于密切遵循当前的证据基础,但在将其作为一线治疗提供或为家长在遮盖疗法和阿托品之间提供选择方面仍存在犹豫。这可能是由于对阿托品的总体疗效、副作用和逆性弱视风险的担忧。或者,正如在医学的其他领域所表明的那样,这可能反映了研究结果转化为临床实践变化的固有延迟。

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