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Cancer: Antitumour immunity gets a boost.

作者信息

Wolchok Jedd D, Chan Timothy A

机构信息

Department of Medicine and the Ludwig Center, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA.

Department of Radiation Oncology and the Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center.

出版信息

Nature. 2014 Nov 27;515(7528):496-8. doi: 10.1038/515496a.

DOI:10.1038/515496a
PMID:25428495
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6592276/
Abstract
摘要

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本文引用的文献

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Checkpoint blockade cancer immunotherapy targets tumour-specific mutant antigens.检查点阻断癌症免疫疗法靶向肿瘤特异性突变抗原。
Nature. 2014 Nov 27;515(7528):577-81. doi: 10.1038/nature13988.
2
Predicting immunogenic tumour mutations by combining mass spectrometry and exome sequencing.通过质谱分析与外显子组测序相结合预测免疫原性肿瘤突变。
Nature. 2014 Nov 27;515(7528):572-6. doi: 10.1038/nature14001.
3
PD-1 blockade induces responses by inhibiting adaptive immune resistance.程序性死亡受体1（PD-1）阻断通过抑制适应性免疫抵抗来诱导反应。
用于癌症免疫治疗的共享新抗原。
Mol Ther Oncol. 2025 Mar 28;33(2):200978. doi: 10.1016/j.omton.2025.200978. eCollection 2025 Jun 18.
4
Docosahexaenoic acid (DHA) impairs hypoxia-induced cellular and exosomal overexpression of immune-checkpoints and immunomodulatory molecules in different subtypes of breast cancer cells.二十二碳六烯酸（DHA）可抑制不同亚型乳腺癌细胞中缺氧诱导的免疫检查点和免疫调节分子的细胞及外泌体过表达。
BMC Nutr. 2024 Mar 4;10(1):41. doi: 10.1186/s40795-024-00844-y.
5
PD-L1/PD-L1 signalling promotes colorectal cancer cell migration ability through RAS/MEK/ERK.PD-L1/PD-L1 信号通过 RAS/MEK/ERK 促进结直肠癌细胞迁移能力。
Clin Exp Pharmacol Physiol. 2022 Dec;49(12):1281-1293. doi: 10.1111/1440-1681.13717. Epub 2022 Sep 15.
6
PDL1Binder: Identifying programmed cell death ligand 1 binding peptides by incorporating next-generation phage display data and different peptide descriptors.程序性死亡配体1结合物：通过整合下一代噬菌体展示数据和不同的肽描述符来鉴定程序性细胞死亡配体1结合肽
Front Microbiol. 2022 Jul 15;13:928774. doi: 10.3389/fmicb.2022.928774. eCollection 2022.
7
Identification of Hypoxia-Related Subtypes, Establishment of Prognostic Models, and Characteristics of Tumor Microenvironment Infiltration in Colon Cancer.结肠癌中缺氧相关亚型的鉴定、预后模型的建立及肿瘤微环境浸润特征
Front Genet. 2022 Jun 17;13:919389. doi: 10.3389/fgene.2022.919389. eCollection 2022.
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A promising Prognostic risk model for advanced renal cell carcinoma (RCC) with immune-related genes.具有免疫相关基因的晚期肾细胞癌（RCC）的有前途的预后风险模型。
BMC Cancer. 2022 Jun 23;22(1):691. doi: 10.1186/s12885-022-09755-2.
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J Cell Mol Med. 2022 May;26(10):2908-2920. doi: 10.1111/jcmm.17305. Epub 2022 Apr 5.
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J Clin Endocrinol Metab. 2022 Jun 16;107(7):1976-1982. doi: 10.1210/clinem/dgac161.
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Predictive correlates of response to the anti-PD-L1 antibody MPDL3280A in cancer patients.癌症患者对抗PD-L1抗体MPDL3280A反应的预测性相关因素。
Nature. 2014 Nov 27;515(7528):563-7. doi: 10.1038/nature14011.
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Genomic and bioinformatic profiling of mutational neoepitopes reveals new rules to predict anticancer immunogenicity.突变新抗原表位的基因组和生物信息学分析揭示了预测抗癌免疫原性的新规则。
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Lancet. 2014 Sep 20;384(9948):1109-17. doi: 10.1016/S0140-6736(14)60958-2. Epub 2014 Jul 15.
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Survival, durable tumor remission, and long-term safety in patients with advanced melanoma receiving nivolumab.纳武利尤单抗治疗晚期黑色素瘤患者的生存、持久肿瘤缓解和长期安全性。
J Clin Oncol. 2014 Apr 1;32(10):1020-30. doi: 10.1200/JCO.2013.53.0105. Epub 2014 Mar 3.
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Immune modulation in cancer with antibodies.癌症的抗体免疫调节。
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