Meyer Michelle R, Shaffer Brian L, Doss Amy E, Cahill Alison G, Snowden Jonathan M, Caughey Aaron B
a University of California at San Francisco , San Francisco , CA , USA .
b Department of Obstetrics and Gynecology , Oregon Health and Science University , Portland , OR , USA , and.
J Matern Fetal Neonatal Med. 2015;28(17):2126-9. doi: 10.3109/14767058.2014.984604. Epub 2014 Dec 23.
To evaluate the ongoing risk of intrauterine fetal demise (IUFD) in fetuses with gastroschisis compared to non-anomalous fetuses.
This was a retrospective cohort study of all births in the United States in 2005-2006, as recorded in the National Center for Health Statistics natality database. Risk of IUFD in fetuses with gastroschisis was compared to non-anomalous fetuses, utilizing total at-risk fetuses as the denominator.
Risk of IUFD in fetuses with gastroschisis was 4.5%, compared to 0.6% in non-anomalous fetuses (p < 0.001). When controlling for gestational age and other confounders, the adjusted odds ratio for IUFD in fetuses with gastroschisis was 7.06 (95% CI: 3.33-14.96). After 32 weeks, risk of IUFD/ongoing pregnancy was greater at each week of gestation in fetuses with gastroschisis.
Risk of IUFD for fetuses with gastroschisis is greater than in non-anomalous fetuses. This risk increases significantly after 32 weeks' gestation. Demographic variables are associated with higher rates of gastroschisis and ultimately IUFD. These data may be useful in consideration of timing of delivery.
评估腹裂胎儿与非异常胎儿相比，宫内胎儿死亡（IUFD）的持续风险。
这是一项对2005 - 2006年美国所有出生情况的回顾性队列研究，数据记录于国家卫生统计中心的出生数据库。将腹裂胎儿的IUFD风险与非异常胎儿进行比较，以所有处于风险中的胎儿作为分母。
腹裂胎儿的IUFD风险为4.5%，而非异常胎儿为0.6%（p < 0.001）。在控制孕周和其他混杂因素后，腹裂胎儿IUFD的调整比值比为7.06（95%可信区间：3.33 - 14.96）。32周后，腹裂胎儿在妊娠的每一周，IUFD/持续妊娠的风险都更高。
腹裂胎儿的IUFD风险高于非异常胎儿。这种风险在妊娠32周后显著增加。人口统计学变量与腹裂发生率较高以及最终的IUFD相关。这些数据可能有助于考虑分娩时机。
