Bali Vandana, Panesar Parmjit S, Bera Manab B
a Biotechnology Research Laboratory, Department of Food Engineering and Technology , Sant Longowal Institute of Engineering and Technology , Longowal , Punjab , India.
Crit Rev Biotechnol. 2016;36(2):204-14. doi: 10.3109/07388551.2014.947916. Epub 2014 Nov 28.
Bacteriocins are proteinaceous, ribosomally synthesized bio-molecules having major roles in food preservation due to their antimicrobial action against food spoilage microorganisms. These have gained importance in the last decades because of increasing interest in natural products and their applications in the field of biopreservation, pharmaceutical, aquaculture, livestock, etc. Their production is quite expensive which includes the cost of synthetic media and downstream processing of which 30% of the total production cost relies on synthetic media and nutritional supplements used for growth of microorganisms. The low cost agro-industrial by-products, rich in nutritional supplements, can act as a good substitute for high valued synthetic media. This review provides comprehensive information on the use of cost effective, renewable agro-industrial by-products as substrates for the production of bacteriocins and their application in food as biopreservatives.
细菌素是核糖体合成的蛋白质类生物分子,由于其对食品腐败微生物具有抗菌作用,在食品保鲜中发挥着重要作用。在过去几十年里,由于人们对天然产物及其在生物保鲜、制药、水产养殖、畜牧业等领域的应用越来越感兴趣,细菌素变得越发重要。它们的生产成本相当高,这包括合成培养基的成本和下游加工成本,其中总生产成本的30%依赖于用于微生物生长的合成培养基和营养补充剂。低成本且富含营养补充剂的农业工业副产品可以很好地替代高价值的合成培养基。本综述提供了关于使用具有成本效益的可再生农业工业副产品作为生产细菌素的底物及其作为生物防腐剂在食品中的应用的全面信息。