Zhang Zhen, Wang Yuanyuan, Zheng Fuwei, Ren Rui, Zhang Shusheng
Shandong Province Key Laboratory of Detection Technology for Tumor Makers, College of Chemistry and Chemical Engineering, Linyi University, Linyi 276005, P. R. China.
Chem Commun (Camb). 2015 Jan 18;51(5):907-10. doi: 10.1039/c4cc08141b. Epub 2014 Nov 28.
A unique four-way helical junction molecule (FHJM) probe was ingeniously designed, and firstly introduced into DNA signal amplification as a novel Surface-enhanced Raman scattering (SERS) probe. Significantly, a new FHJM-SERS method was successfully developed for lysozyme detection with high sensitivity and specificity.
一种独特的四向螺旋连接分子(FHJM)探针被巧妙设计,并首次作为新型表面增强拉曼散射(SERS)探针引入DNA信号放大。值得注意的是,一种用于溶菌酶检测的具有高灵敏度和特异性的新型FHJM-SERS方法被成功开发。