Ouyang P C
Department of Obstetrics and Gynecology, College Medicine, Taiwan.
Gan To Kagaku Ryoho. 1989 Apr;16(4 Pt 2-2):1544-52.
Advances in the management of gestational trophoblastic tumor have been made during the last three decades. Individualization of the therapy is one of the major advances. A number of risk factors has proved to predict accurately the prognosis of each patient. A few systems were currently in use, but difficult in putting them to practical use in the different geographical areas. At National Taiwan University Hospital from 1965 to 1979, 65 patients treated by chemotherapy were analyzed with respect of various prognostic factors. The score was assigned according to the mortality rate of each item to each prognostic factor, and thus established a scoring system which is suitable for the use in Taiwan. After establishment of our scoring system, 51 patients from 1980 to 1986 were treated according to the system and the appropriate therapeutic regimens. The outcome of these patients and toxicity of the different therapeutic regimens are presented.
在过去三十年中，妊娠滋养细胞肿瘤的管理取得了进展。治疗个体化是主要进展之一。一些风险因素已被证明能准确预测每位患者的预后。目前有一些系统在使用，但在不同地理区域难以实际应用。1965年至1979年在台湾大学医院，对65例接受化疗的患者的各种预后因素进行了分析。根据每个预后因素中各项目的死亡率为其打分，从而建立了一个适用于台湾的评分系统。在我们的评分系统建立后，1980年至1986年的51例患者按照该系统及适当的治疗方案进行了治疗。本文介绍了这些患者的治疗结果以及不同治疗方案的毒性。
