Shi Shuyuan, Yang Jingkui, Sun Daqiang
Department of Thoracic Surgery, Second Hospital of Tianjin Medical University, Tianjin 300211, P.R. China.
Department of Thoracic Surgery, Tianjin Chest Hospital, Tianjin 300051, P.R. China.
Oncol Lett. 2015 Jan;9(1):375-380. doi: 10.3892/ol.2014.2649. Epub 2014 Oct 30.
Colorectal cancer (CRC) is one of the most common malignancies in the world and distant metastasis is the main cause of cancer-related mortality. Percutaneous computed tomography (CT) guided radioactive I seed implantation (CTRISI) is a minimally invasive technique used to treat pulmonary metastases in CRC patients. In the present study, following colorectal cancer resection, six patients with pulmonary metastases were treated with computed tomography (CT)-guided percutaneous implantation of radioactive I seeds. At six months following seed implantation, CT examination was performed and compared with the images captured prior to the treatment. Of the total 13 lesions, four had disappeared, eight were reduced by >50% and one was enlarged, indicating that the local control rate was 92.3% (12/13). Overall, two patients developed intraoperative pneumothorax and one experienced hemoptysis subsequent to the procedure. Following a median follow-up period of 31 months, no local recurrence was observed in 12 of the metastatic lesions. The mean survival time was 32.7 months and the median survival time was 31 months.
结直肠癌（CRC）是世界上最常见的恶性肿瘤之一，远处转移是癌症相关死亡的主要原因。经皮计算机断层扫描（CT）引导下放射性碘粒子植入术（CTRISI）是一种用于治疗CRC患者肺转移的微创技术。在本研究中，6例结直肠癌切除术后出现肺转移的患者接受了CT引导下经皮放射性碘粒子植入治疗。粒子植入后6个月，进行CT检查并与治疗前采集的图像进行比较。在总共13个病灶中，4个消失，8个缩小>50%，1个增大，表明局部控制率为92.3%（12/13）。总体而言，2例患者术中出现气胸，1例术后出现咯血。中位随访期31个月后，12个转移病灶未观察到局部复发。平均生存时间为32.7个月，中位生存时间为31个月。
