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人类小脑:生理神经解剖学综述

The human cerebellum: a review of physiologic neuroanatomy.

作者信息

Roostaei Tina, Nazeri Arash, Sahraian Mohammad Ali, Minagar Alireza

机构信息

MS Research Center, Neuroscience Institute, Sina Hospital, Tehran University of Medical Sciences, Hassan Abad Square, Tehran 1136746911, Iran; Interdisciplinary Neuroscience Research Program, Tehran University of Medical Sciences, Poursina Street, Tehran 1417863181, Iran.

MS Research Center, Neuroscience Institute, Sina Hospital, Tehran University of Medical Sciences, Hassan Abad Square, Tehran 1136746911, Iran; Interdisciplinary Neuroscience Research Program, Tehran University of Medical Sciences, Poursina Street, Tehran 1417863181, Iran; Kimel Family Translational Imaging-Genetics Research Laboratory, Centre for Addiction and Mental Health, University of Toronto, 250 College Street, Toronto ON M5T 1R8, Canada.

出版信息

Neurol Clin. 2014 Nov;32(4):859-69. doi: 10.1016/j.ncl.2014.07.013. Epub 2014 Oct 24.

Abstract

The cerebellum resides in the posterior cranial fossa dorsal to the brainstem and has diverse connections to the cerebrum, brain stem, and spinal cord. It is anatomically and physiologically divided into distinct functional compartments and is composed of highly regular arrays of neuronal units, each sharing the same basic cerebellar microcircuitry. Its circuitry is critically involved in motor control and motor learning, and its role in nonmotor cognitive and affective functions is becoming increasingly recognized. This article describes the cerebellar gross and histologic neuroanatomy in relation to its function, and the relevance of cerebellar circuitry and firing patterns to motor learning.

摘要

小脑位于脑干背侧的后颅窝内,与大脑、脑干和脊髓有着多样的连接。在解剖学和生理学上,它被划分为不同的功能区,由高度规则排列的神经元单元组成,每个单元都共享相同的基本小脑微环路。其神经环路在运动控制和运动学习中起着关键作用,并且它在非运动认知和情感功能中的作用也越来越受到认可。本文描述了与功能相关的小脑大体和组织学神经解剖结构,以及小脑神经环路和放电模式与运动学习的相关性。

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