Christiansen H M, Borris L C, Lassen M R
Ugeskr Laeger. 1989 May 22;151(21):1302-5.
The theory for employment of low molecular weight heparin and the material concerning employment of low molecular weight heparin hitherto published is reviewed. To date, it has been demonstrated that low molecular weight heparin has the same antithrombotic efficacy as unfractionated heparin and its half life is approximately twice as long. This implies that adequate thrombosis prophylaxis can be obtained with a single daily dose.
本文回顾了低分子量肝素的应用理论以及迄今已发表的有关低分子量肝素应用的资料。迄今为止,已经证实低分子量肝素具有与普通肝素相同的抗血栓形成功效,并且其半衰期大约是普通肝素的两倍。这意味着每日单次给药即可获得足够的血栓预防效果。