Sardana Kabir, Goel Khushbu
Maulana Azad Medical College and Lok Nayak Hospital, New Delhi, India.
Maulana Azad Medical College and Lok Nayak Hospital, New Delhi, India.
Clin Dermatol. 2014 Nov-Dec;32(6):817-26. doi: 10.1016/j.clindermatol.2014.02.022. Epub 2014 Oct 29.
Nasal septal ulceration can have multiple etiologies. Determining the exact cause depends on who the consulting specialist is, who could either be the ENT surgeon or the dermatologist. The common causes are infections (tuberculosis, leprosy, leishmaniasis), vasculitis (Wegener's granulomatosis and Churg-Strauss syndrome), and lupus erythematosus. Traumatic causes and malignancy can also be seen in tertiary referral centers. The diagnosis often requires thorough investigations and multiple tissue specimens from various sites, and in chronic cases, a suspicion of lymphoma should be considered. Apart from disease-specific therapy, a multidisciplinary approach is required in most cases to tackle the cosmetic disfigurement.
鼻中隔溃疡可有多种病因。确定确切病因取决于会诊的专科医生,可能是耳鼻喉科外科医生或皮肤科医生。常见病因包括感染(结核病、麻风病、利什曼病)、血管炎(韦格纳肉芽肿和变应性肉芽肿性血管炎)以及红斑狼疮。在三级转诊中心也可见到创伤性病因和恶性肿瘤。诊断通常需要进行全面检查并从不同部位获取多个组织标本,对于慢性病例,应考虑淋巴瘤的可能性。除了针对特定疾病的治疗外,大多数情况下需要采取多学科方法来解决外观毁损问题。