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一种明确的管理策略可改善Fontan手术后的早期结局:波特兰方案。

A defined management strategy improves early outcomes after the Fontan procedure: the PORTLAND protocol.

作者信息

Sunstrom Rachel E, Muralidaran Ashok, Gerrah Rabin, Reed Richard D, Good Milon K, Armsby Laurie R, Rekito Andrew J, Zubair M Mujeeb, Langley Stephen M

机构信息

Division of Pediatric and Congenital Cardiac Surgery, Doernbecher Children's Hospital, Oregon Health and Science University, Portland, Oregon.

Division of Pediatric and Congenital Cardiac Surgery, Doernbecher Children's Hospital, Oregon Health and Science University, Portland, Oregon.

出版信息

Ann Thorac Surg. 2015 Jan;99(1):148-55. doi: 10.1016/j.athoracsur.2014.06.121. Epub 2014 Nov 18.

Abstract

BACKGROUND

Patients undergoing the Fontan procedure may have extended hospital stay due to various postoperative factors including prolonged chest tube drainage. Our aim was to determine the efficacy of our Fontan management protocol in reducing chest tube drainage and length of stay.

METHODS

Patients who underwent a Fontan procedure at our institution from June 2008 to September 2013 were analyzed (n = 42). We currently manage our patients according to the PORTLAND protocol: Peripheral vasodilation, Oxygen, Restriction of fluids, Technique of surgery, Low-fat diet, Anticoagulation (including antithrombin III management), No ventilator, and Diuretics. Group A (n = 28) had surgery prior to initiation of this protocol; group B (n = 14) had surgery during the current protocol era.

RESULTS

The median number of chest tube days was lower in group B (6 vs 11 days, p < 0.001) as was the total indexed drainage (126 vs 259 mL/kg, p < 0.001). Patients in group B had shorter intensive care unit length of stay (4 vs 7 days, p = 0.004) and hospital length of stay (8 vs 13 days, p = 0.001). Group B had higher preoperative common atrial pressures (7.0 vs 5.8 mm Hg, p = 0.017), end-diastolic pressures (9 vs 7 mm Hg, p = 0.026), and trended toward higher pulmonary artery pressures (11.5 vs 9.5 mm Hg, p = 0.077). There was no statistically significant difference in age, weight, transpulmonary gradient, or pulmonary vascular resistance between groups.

CONCLUSIONS

The PORTLAND protocol has improved early outcomes after the Fontan procedure. Chest tube drainage and duration, and both intensive care unit and hospital length of stay have been reduced since initiation of this protocol.

摘要

背景

接受Fontan手术的患者可能因多种术后因素,包括胸腔闭式引流时间延长,导致住院时间延长。我们的目的是确定我们的Fontan管理方案在减少胸腔闭式引流和住院时间方面的疗效。

方法

对2008年6月至2013年9月在我院接受Fontan手术的患者进行分析(n = 42)。我们目前根据PORTLAND方案管理患者:外周血管扩张、吸氧、限制液体摄入、手术技术、低脂饮食、抗凝(包括抗凝血酶III管理)、不使用呼吸机和利尿剂。A组(n = 28)在该方案启动前接受手术;B组(n = 14)在当前方案实施期间接受手术。

结果

B组胸腔闭式引流天数中位数较低(6天对11天,p < 0.001),总指数引流量也较低(126 mL/kg对259 mL/kg,p < 0.001)。B组患者在重症监护病房的住院时间较短(4天对7天,p = 0.004),住院时间也较短(8天对13天,p = 0.001)。B组术前平均心房压较高(7.0 mmHg对5.8 mmHg,p = 0.017),舒张末期压力较高(9 mmHg对7 mmHg,p = 0.026),肺动脉压力有升高趋势(11.5 mmHg对9.5 mmHg,p = 0.077)。两组在年龄、体重、跨肺压差或肺血管阻力方面无统计学显著差异。

结论

PORTLAND方案改善了Fontan手术后的早期结局。自该方案启动以来,胸腔闭式引流的量和持续时间以及重症监护病房和住院时间均有所减少。

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