过渡到移除：左心室辅助装置治疗的范式转变
Bridge to removal: a paradigm shift for left ventricular assist device therapy.
作者信息
Selzman Craig H, Madden Jesse L, Healy Aaron H, McKellar Stephen H, Koliopoulou Antigone, Stehlik Josef, Drakos Stavros G
机构信息
Division of Cardiothoracic Surgery, University of Utah School of Medicine, Salt Lake City, Utah.
Division of Cardiothoracic Surgery, University of Utah School of Medicine, Salt Lake City, Utah.
出版信息
Ann Thorac Surg. 2015 Jan;99(1):360-7. doi: 10.1016/j.athoracsur.2014.07.061. Epub 2014 Nov 14.
Abstract
Ventricular assist devices have become standard therapy for patients with advanced heart failure either as a bridge to transplantation or destination therapy. Despite the functional and biologic evidence of reverse cardiac remodeling, few patients actually proceed to myocardial recovery, and even fewer to the point of having their device explanted. An enhanced understanding of the biology and care of the mechanically supported patient has redirected focus on the possibility of using ventricular assist devices as a bridge to myocardial recovery and removal. Herein, we review the current issues and approaches to transforming myocardial recovery to a practical reality.
摘要
心室辅助装置已成为晚期心力衰竭患者的标准治疗手段，可作为移植过渡或终末治疗。尽管有功能和生物学证据表明心脏逆向重构，但实际上很少有患者能实现心肌恢复，更少有人能达到移除装置的程度。对机械支持患者的生物学特性和护理的深入理解，已将重点重新转向将心室辅助装置用作心肌恢复和移除桥梁的可能性。在此，我们回顾当前将心肌恢复转化为实际现实的问题和方法。
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