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西班牙 2000 至 2009 年首次检测 HIV 者中的 HIV 检测、流行率及高危人群中发病率的变化趋势:EPI-VIH 研究。

Trends in HIV testing, prevalence among first-time testers, and incidence in most-at-risk populations in Spain: the EPI-VIH Study, 2000 to 2009.

机构信息

Plan Nacional sobre el sida, Ministerio de Sanidad, Servicios Sociales e Igualdad, Madrid, Spain.

出版信息

Euro Surveill. 2014 Nov 27;19(47):20971. doi: 10.2807/1560-7917.es2014.19.47.20971.

DOI:10.2807/1560-7917.es2014.19.47.20971
PMID:25443036
Abstract

During 2000 to 2009, data on people undergoing HIV testing and on those newly diagnosed with HIV were collected in a network of 20 Spanish clinics specialising in sexually transmitted infections and/or HIV testing and counselling. The number of tests performed, overall and disaggregated by different variables, was obtained. HIV prevalence among first-time testers and HIV incidence among repeat testers were calculated. To evaluate trends, joinpoint regression models were fitted. In total, 236,939 HIV tests were performed for 165,745 individuals. Overall HIV prevalence among persons seeking HIV testing was 2.5% (95% CI: 2.4 to 2.6). Prevalence was highest in male sex workers who had sex with other men (19.0% (95% CI: 16.7 to 21.4)) and was lowest in female sex workers (0.8% (95% CI: 0.7 to 0.9)). Significant trends in prevalence were observed in men who have sex with men (MSM) (increasing) and heterosexual individuals (decreasing). The incidence analysis included 30,679 persons, 64,104 person-years (py) of follow-up and 642 seroconversions. The overall incidence rate (IR) was 1.0/100 py (95% CI: 0.9/100 to 1.1/100). Incidence was significantly higher in men and transgender females than in women (1.8/100 py (95% CI: 1.6 to 1.9), 1.2/100 py (95% CI: 0.5 to 2.8) and 0.1/100 py (95% CI: 0.09 to 0.2) respectively) and increased with age until 35–39 years. IRs in MSM and people who inject drugs were significantly greater than in heterosexual individuals (2.5/100 py (95% CI: 2.3 to 2.7), 1.6/100 py (95% CI: 1.1 to 2.2) and 0.1/100 py (95% CI: 0.09 to 0.2) respectively), and an upward trend was observed in MSM. Our results call for HIV prevention to be reinforced in MSM and transgender women in Spain.

摘要

2000 年至 2009 年期间,在西班牙的 20 家性传播感染和/或艾滋病毒检测和咨询专门诊所网络中收集了接受艾滋病毒检测和新诊断为艾滋病毒感染者的数据。获得了进行的检测总数以及按不同变量分类的检测数量。计算了首次检测者的艾滋病毒流行率和重复检测者的艾滋病毒发病率。为了评估趋势,拟合了连接点回归模型。共对 165745 人进行了 236939 次艾滋病毒检测。寻求艾滋病毒检测者的总体艾滋病毒流行率为 2.5%(95%CI:2.4-2.6)。男男性行为者(MSM)中艾滋病毒流行率最高(19.0%(95%CI:16.7-21.4)),性工作者(FSW)中艾滋病毒流行率最低(0.8%(95%CI:0.7-0.9))。男男性行为者(MSM)和异性恋者中观察到艾滋病毒流行率呈显著趋势(增加和减少)。发病率分析包括 30679 人,64104 人年(py)随访和 642 例血清转换。总发病率(IR)为 1.0/100 py(95%CI:0.9-1.1/100)。男性和跨性别女性的发病率明显高于女性(1.8/100 py(95%CI:1.6-1.9),1.2/100 py(95%CI:0.5-2.8)和 0.1/100 py(95%CI:0.09-0.2)),并且随着年龄的增长到 35-39 岁而增加。男男性行为者和注射毒品者的发病率明显高于异性恋者(2.5/100 py(95%CI:2.3-2.7),1.6/100 py(95%CI:1.1-2.2)和 0.1/100 py(95%CI:0.09-0.2)),并且男男性行为者的发病率呈上升趋势。我们的结果呼吁在西班牙加强对男男性行为者和跨性别女性的艾滋病毒预防。

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