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[化疗、放疗、免疫治疗及中药联合治疗小细胞肺癌]

[Combined modality treatment of small cell lung cancer by chemotherapy, radiotherapy, immunotherapy and Chinese traditional medicine].

作者信息

Cha R J

出版信息

Zhonghua Jie He He Hu Xi Za Zhi. 1989 Feb;12(1):41-4, 63.

PMID:2544304
Abstract

The combined modality treatment consisted mainly of long-term intermittent combination chemotherapy (VCMB being in the majority) and radiotherapy combined with immunotherapy as well as Chinese traditional medicine. The patients treated with this therapy were observed in 1974-1986, till successive fifty, and followed up to January 1988. They were of the stage I, II, III and IV including 3, 10, 20 and 17 patients respectively. The complete remission rate was 54% (27/50); the partial remission rate, 40% (20/50). The total effective rate was 94% (47/50). According to the calculation of life-table, 2-year survival rate for the stage I-II (n = 13) was 76.2%; 5-year survival rate, 55.5%. For the stage III (n = 20), 2-year survival rate was 46.9%; 5-year, 18.8%. By long-term combined modality, the survival rate has obviously improved, and the possibility of cure has evidently increased.

摘要

综合治疗主要包括长期间歇性联合化疗(以VCMB为主)、放疗、免疫治疗以及中药。1974年至1986年对接受该疗法的患者进行观察,持续50例,随访至1988年1月。患者包括Ⅰ、Ⅱ、Ⅲ、Ⅳ期,分别为3例、10例、20例和17例。完全缓解率为54%(27/50);部分缓解率为40%(20/50)。总有效率为94%(47/50)。根据寿命表计算,Ⅰ - Ⅱ期(n = 13)的2年生存率为76.2%;5年生存率为55.5%。Ⅲ期(n = 20)的2年生存率为46.9%;5年生存率为18.8%。通过长期综合治疗,生存率明显提高,治愈的可能性显著增加。

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