Mitchell Sarah A, Brucker Benjamin M, Kaefer Daniela, Aponte Margarita, Rosenblum Nirit, Kelly Christopher, Hickling Duane, Nitti Victor W
Department of Urology, New York University Langone Medical Center, New York, NY.
Division of Urology, Department of Surgery, Faculty of Medicine, University of Ottawa, ON, Canada.
Urology. 2014 Nov;84(5):1039-43. doi: 10.1016/j.urology.2014.07.014. Epub 2014 Oct 24.
To explain what role urinary urgency has on urinary frequency in patients with overactive bladder (OAB).
We prospectively enrolled 102 patients with OAB over a 6-week period. Patients were assessed with the OAB-q and a pilot questionnaire to identify which urinary symptoms were most bothersome and what underlying cause subjects attributed urinary frequency to. Associations between epidemiologic characteristics, OAB-q scores, and subject responses to the pilot questionnaire, were examined for statistical significance with the Pearson chi square test.
The study population comprised 85% women and 15% men, with mean age 67.4 years and mean OAB-q score 54. Subjects reported their most bothersome symptom was: frequency 24.5%, urgency or urgency incontinence 48.0%, nocturia 27.5%. Of the patients most bothered by frequency, 64% identified the International Continence Society definition of urgency or "fear of leakage" as the underlying reason for their frequency. Overall, 82.4% and 48.0% of patients reported urgency or urgency incontinence as a symptom and most bothersome symptom respectively. However, when patients were specifically asked what drives their urinary frequency, these percentages increased to 89.2% and 63.7%.
This pilot study confirms that urgency is a large factor underlying the drive to void frequently in OAB, even when patients do not admit to urgency as the most bothersome symptom.
解释尿急在膀胱过度活动症(OAB)患者的尿频中所起的作用。
我们在6周内前瞻性招募了102名OAB患者。使用OAB-q和一份初步调查问卷对患者进行评估,以确定哪些泌尿系统症状最困扰患者,以及患者将尿频归因于何种潜在原因。采用Pearson卡方检验来检验流行病学特征、OAB-q评分与患者对初步调查问卷的回答之间的关联是否具有统计学意义。
研究人群包括85%的女性和15%的男性,平均年龄67.4岁,平均OAB-q评分为54分。患者报告他们最困扰的症状为:尿频占24.5%,尿急或急迫性尿失禁占48.0%,夜尿症占27.5%。在受尿频困扰最大的患者中,64%认为国际尿控协会对尿急的定义或“害怕漏尿”是其尿频的根本原因。总体而言,分别有82.4%和48.0%的患者报告尿急或急迫性尿失禁为一种症状和最困扰的症状。然而,当专门询问患者是什么导致他们尿频时,这些百分比分别增至89.2%和63.7%。
这项初步研究证实,尿急是OAB患者频繁排尿的一个重要潜在因素,即使患者不承认尿急是最困扰的症状。