Miura John T, Gamblin T Clark
Division of Surgical Oncology, Medical College of Wisconsin, 9200 West Wisconsin Avenue, Milwaukee, WI 53226, USA.
Division of Surgical Oncology, Department of Surgery, Medical College of Wisconsin, 9200 West Wisconsin Avenue, Milwaukee, WI 53226, USA.
Surg Oncol Clin N Am. 2015 Jan;24(1):149-66. doi: 10.1016/j.soc.2014.09.004. Epub 2014 Oct 7.
Management of liver malignancies, both primary and metastatic, requires a host of treatment modalities when attempting to prolong survival. Although surgical resection and transplantation continue to offer the best chance for a cure, most patients are not amenable to these therapies because of their advanced disease at presentation. Taking advantage of the unique blood supply of the liver, transarterial chemoembolization has emerged as an alternative and effective therapy for unresectable tumors. In this article, the current role along with future perspectives of transarterial chemoembolization for hepatocellular carcinoma, intrahepatic cholangiocarcinoma, and colorectal liver metastasis are discussed.
在试图延长生存期时，原发性和转移性肝脏恶性肿瘤的管理需要一系列治疗方式。尽管手术切除和移植仍然提供了治愈的最佳机会，但大多数患者由于就诊时疾病已处于晚期，无法接受这些治疗。利用肝脏独特的血液供应，经动脉化疗栓塞已成为不可切除肿瘤的一种替代且有效的治疗方法。本文讨论了经动脉化疗栓塞在肝细胞癌、肝内胆管癌和结直肠癌肝转移中的当前作用以及未来前景。
