School of Public Health, State University of New York, University at Albany, Rensselaer, NY.
School of Public Health, State University of New York, University at Albany, Rensselaer, NY; Rollins School of Public Health, Emory University, Atlanta, GA.
J Pediatr. 2015 Jan;166(1):151-6. doi: 10.1016/j.jpeds.2014.09.013. Epub 2014 Oct 16.
To identify children vaccinated following an alternative vaccine schedule using immunization information system data and determine the impact of alternative schedule use on vaccine coverage.
Children born in New York State, outside New York City, between January 1, 2009 and August 14, 2011 were assessed for vaccination patterns consistent with use of an alternative schedule. Children who by 9 months of age had at least 3 vaccination visits recorded in the statewide mandatory immunization information system after 41 days of age were classified as either attempting to conform to the Centers for Disease Control and Prevention published recommended vaccination schedule or an alternative schedule. The number of vaccination visits and up-to-date status at age 9 months were compared between groups.
Of the 222 628 children studied, the proportion of children following an alternative schedule was 25%. These children were significantly less likely to be up-to-date at age 9 months (15%) compared with those conforming to the routine schedule (90%, P < .05). Children following an alternative schedule on average had about 2 extra vaccine visits compared with children following a routine schedule (P < .05).
Almost 1 in 4 children in this study appear to be intentionally deviating from the routine schedule. Intentional deviation leads to poor vaccination coverage leaving children vulnerable to infection and increasing the potential for vaccine-preventable disease outbreaks.
利用免疫信息系统数据识别按替代疫苗接种时间表接种疫苗的儿童,并确定替代接种时间表的使用对疫苗接种率的影响。
2009 年 1 月 1 日至 2011 年 8 月 14 日期间,在纽约市以外的纽约州出生的儿童评估其是否符合替代接种时间表。在 41 天龄后,9 个月龄时至少有 3 次接种记录的儿童被归类为试图符合疾病控制和预防中心发布的推荐疫苗接种时间表或替代时间表。比较两组之间 9 个月龄时的接种次数和最新状态。
在 222628 名研究儿童中,有 25%的儿童遵循替代时间表。与遵循常规时间表的儿童(90%)相比,这些儿童在 9 个月时的最新接种率明显较低(15%,P<.05)。与遵循常规时间表的儿童相比,遵循替代时间表的儿童平均多进行了约 2 次疫苗接种(P<.05)。
在这项研究中,近 1/4 的儿童似乎有意偏离常规时间表。有意偏离会导致疫苗接种率不佳,使儿童易受感染,并增加疫苗可预防疾病爆发的可能性。