Peleg Noam, Zevit Noam, Shamir Raanan, Chodick Gabriel, Levy Itzhak
Sackler Faculty of Medicine, Tel.: Aviv University, Tel: Aviv, Petach Tikva, Israel.
Sackler Faculty of Medicine, Tel.: Aviv University, Tel: Aviv, Petach Tikva, Israel; Institute of Gastroenterology, Nutrition and Liver Diseases, Petach Tikva, Israel.
Vaccine. 2015 Jan 1;33(1):182-6. doi: 10.1016/j.vaccine.2014.10.086. Epub 2014 Nov 11.
Despite advances in the treatment and prevention of influenza, it is still considered an important cause of morbidity and mortality worldwide. Annual vaccination is the safest and most effective mean of prevention. Our study aims were to explore the uptake of influenza vaccination among children with gastrointestinal disorders, and to characterize non-adherent patients.
The present cross-sectional study included parents of pediatric patients attending the Gastroenterology Institute at Schneider Children's Medical Center of Israel between September and October 2011. Parents were asked to complete a questionnaire concerning demographic and clinical parameters, influenza vaccination of the child, and reasons for not vaccinating the child, when appropriate.
The study population included 273 patients (50% female), with a median age of 10 years (range, 2-18 years). Overall, the rate of seasonal influenza vaccination was 30.8%. Higher rates were found among immunosuppressed patients (46.1%), and in patients with inflammatory bowel disease (50%). There was no significant effect of patient age, gender, ethnic origin or parental level of education on the vaccination rate. Vaccination rates were significantly associated with parents' information and knowledge of, as well as their personal beliefs regarding the vaccine (P<0.001).
Influenza vaccination rates are relatively low in the pediatric population attending gastroenterology clinics, in both high- and low-risk groups. The importance of parental knowledge in compliance with influenza vaccination of children should prompt general pediatricians and gastroenterologists to discuss and address the common misconceptions regarding the vaccine.
尽管在流感治疗和预防方面取得了进展，但它在全球范围内仍是发病和死亡的重要原因。年度疫苗接种是最安全、最有效的预防手段。我们的研究目的是探讨患有胃肠道疾病儿童的流感疫苗接种情况，并对未接种疫苗的患者进行特征描述。
本横断面研究纳入了2011年9月至10月在以色列施耐德儿童医学中心胃肠病研究所就诊的儿科患者的家长。要求家长填写一份问卷，内容涉及人口统计学和临床参数、孩子的流感疫苗接种情况以及在适当情况下孩子未接种疫苗的原因。
研究人群包括273名患者（50%为女性），中位年龄为10岁（范围2 - 18岁）。总体而言，季节性流感疫苗接种率为30.8%。免疫抑制患者中的接种率较高（46.1%），炎症性肠病患者中的接种率为50%。患者年龄、性别、种族或父母教育水平对疫苗接种率没有显著影响。疫苗接种率与家长对疫苗的信息了解、知识掌握以及个人信念显著相关（P<0.001）。
在胃肠病诊所就诊的儿科人群中，无论高危组还是低危组，流感疫苗接种率都相对较低。家长知识在儿童流感疫苗接种依从性方面的重要性，应促使普通儿科医生和胃肠病医生讨论并解决有关疫苗的常见误解。
