Disciplines of Paediatrics and Public Health, School of Paediatrics and Reproductive Health, School of Population Health and Clinical Practice, University of Adelaide, Adelaide, SA, Australia.
Hum Vaccin Immunother. 2012 May;8(5):662-7. doi: 10.4161/hv.19478. Epub 2012 May 1.
To assess parental vaccine safety views and future vaccination decisions after an adverse event following immunization (AEFI) experienced by their child. A cross-sectional telephone survey was conducted of parents of children aged 0-7 y, identified in AEFI reports submitted to the South Australian Immunization Section, Department Health. The reports included childhood National Immunization Program (NIP), seasonal or pandemic influenza vaccines. Interviews were conducted following a national suspension of the 2010 seasonal trivalent influenza (STIV) vaccine. Parental attitudes toward vaccine safety, reasons for reporting the AEFI and impact on future vaccination intent were assessed. Of 179 parents interviewed, 88% were confident in the safety of vaccines in general. Parents reporting an AEFI to the STIV were more likely to state the event had influenced future vaccination decisions than the NIP vaccine reporters (65% vs 14%, p < 0.001), with 63% stating refusal or hesitance to re-vaccinate their children against influenza. Media reports of the 2010 STIV program suspension was the most common reason for reporting an AEFI for parents of children who received an influenza vaccination. The AEFI experience did not impact on parental decision to continue with routine childhood NIP schedules, regardless of whether children received influenza or NIP vaccines. In contrast, most parents whose child experienced an AEFI to the 2010 STIV stated decreased confidence in the safety of influenza vaccines, which is likely to have impacted on the uptake of seasonal influenza vaccination in 2011. Addressing influenza vaccine safety concerns to promote influenza vaccination in the community is required.
为了评估父母在孩子发生疫苗接种不良反应（AEFI）后的疫苗安全性看法和未来的疫苗接种决定。对在南澳大利亚免疫科向卫生部提交的 AEFI 报告中确定的 0-7 岁儿童的父母进行了横断面电话调查。报告包括儿童国家免疫计划（NIP）、季节性或大流行性流感疫苗。在暂停使用 2010 年季节性三价流感（STIV）疫苗后进行了访谈。评估了父母对疫苗安全性的态度、报告 AEFI 的原因以及对未来疫苗接种意愿的影响。在接受采访的 179 位父母中，88%的人对疫苗的总体安全性有信心。向 STIV 报告 AEFI 的父母比向 NIP 疫苗报告者更有可能表示该事件影响了未来的疫苗接种决定（65%对 14%，p<0.001），其中 63%表示拒绝或犹豫为孩子再次接种流感疫苗。媒体对 2010 年 STIV 计划暂停的报道是报告接种流感疫苗儿童 AEFI 的最常见原因。AEFI 经历并没有影响父母继续进行常规儿童 NIP 计划的决定，无论孩子是否接种了流感或 NIP 疫苗。相比之下，大多数孩子经历了 2010 年 STIV 的 AEFI 的父母表示对流感疫苗的安全性信心下降，这可能会影响 2011 年季节性流感疫苗的接种率。需要解决流感疫苗安全性问题，以促进社区内的流感疫苗接种。
