从通关藤根中分离得到的新多氧孕甾烷糖苷。

New polyoxypregnane glycosides from the roots of Marsdenia tenacissima.

作者信息

Pang Xu, Kang Li-Ping, Yu He-Shui, Zhao Yang, Han Li-Feng, Zhang Jie, Xiong Cheng-Qi, Zhang Li-Xia, Yu Li-Yan, Ma Bai-Ping

机构信息

Beijing Institute of Radiation Medicine, Beijing 100850, China; Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100050, China.

State Key Laboratory of Dao-di Herbs, National Resource Center for Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China; Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China.

出版信息

Steroids. 2015 Jan;93:68-76. doi: 10.1016/j.steroids.2014.11.004. Epub 2014 Nov 28.

DOI:10.1016/j.steroids.2014.11.004

PMID:25447796

Abstract

For the first time, a systematic phytochemical study was performed on the roots of Marsdenia tenacissima. Finally, sixteen new polyoxypregnane glycosides, marstenacissides A1-A7 (1-7) and marstenacissides B1-B9 (8-16), were isolated from M. tenacissima roots. The structures of these new compounds were established by various spectroscopic techniques, including 1D and 2D NMR spectroscopy and mass spectrometry.

摘要

首次对通光藤的根进行了系统的植物化学研究。最终，从通光藤根中分离出16种新的多氧孕甾烷糖苷，即通光藤苷A1 - A7（1 - 7）和通光藤苷B1 - B9（8 - 16）。这些新化合物的结构通过各种光谱技术确定，包括一维和二维核磁共振光谱以及质谱。