Wang Xiang, Yan Yuanliang, Chen Xi, Zeng Shuangshuang, Qian Long, Ren Xinxin, Wei Jie, Yang Xue, Zhou Yangying, Gong Zhicheng, Xu Zhijie
Department of Pharmacy, Xiangya Hospital, Central South University, Changsha, China.
National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, China.
Front Oncol. 2018 Oct 23;8:473. doi: 10.3389/fonc.2018.00473. eCollection 2018.
(MT), a traditional Chinese herbal medicine, has long been used for thousands of years to treat asthma, tracheitis, rheumatism, etc. An increasing number of recent studies have focused on the antitumor effects of MT. The effects of MT on cancer are the result of various activated signaling pathways and inhibiting factors and the high expression levels of regulatory proteins. MT can inhibit different cancer types including non-small cell lung cancer (NSCLC), malignant tumors, hepatic carcinoma, and so on. This article mainly focuses on the activities and mechanisms of MT. In addition, the efficacy and toxicity of MT are also discussed. Further studies of MT are required for improved medicinal utilization.
丹参,一种传统的中草药,数千年来一直被用于治疗哮喘、气管炎、风湿病等。近年来,越来越多的研究聚焦于丹参的抗肿瘤作用。丹参对癌症的作用是多种激活的信号通路、抑制因子以及调节蛋白高表达水平的结果。丹参可以抑制包括非小细胞肺癌(NSCLC)、恶性肿瘤、肝癌等不同类型的癌症。本文主要聚焦于丹参的活性和作用机制。此外,还讨论了丹参的疗效和毒性。为了提高药物利用率,需要对丹参进行进一步研究。