Carvalho de Lucena Kleber F, Rodrigues Jussara M N, Campos Édipo M, Dantas Antônio F M, Pfister James A, Cook Daniel, Medeiros Rosane M T, Riet-Correa Franklin
Veterinary Hospital, Federal University of Campina Grande, Patos, CEP 58700-310 Paraíba, Brazil.
Poisonous Plant Research Laboratory, Agriculture Research Service, U.S. Department of Agriculture, 1150 E. 1400 N., Logan, UT 84341, United States.
Toxicon. 2014 Dec 15;92:129-32. doi: 10.1016/j.toxicon.2014.10.019. Epub 2014 Oct 23.
Two experiments, each with 10 pregnant ewes (8 treated and 2 controls) were performed to determine if nursing lambs of lactating ewes become intoxicated when the ewes ingest Ipomoea asarifolia but do not show clinical signs themselves. In the first experiment the sheep grazed I. asarifolia in the field while in the second, sheep were maintained in individual bays consuming dry I. asarifolia at 10% and 20% into their ration. In both experiments the lambs remained confined, consuming only their mother's milk. Four of 8 lambs in the grazing experiment and the 4 nursing lambs from the ewes given 20% I. asarifolia showed signs of I. asarifolia poisoning. These results confirm that the tremorgenic compound of I. asarifolia or its toxic metabolites are eliminated in milk and can intoxicate nursing lambs.
进行了两项实验,每项实验有10只怀孕母羊(8只接受处理,2只为对照),以确定当哺乳母羊摄入细辛叶番薯但自身未表现出临床症状时,其哺乳的羔羊是否会中毒。在第一项实验中,绵羊在田间啃食细辛叶番薯,而在第二项实验中,绵羊被单独饲养在畜栏中,其日粮中含有10%和20%的干燥细辛叶番薯。在两项实验中,羔羊均被圈养,仅食用母乳。放牧实验中的8只羔羊中有4只以及日粮中含有20%细辛叶番薯的母羊所哺乳的4只羔羊出现了细辛叶番薯中毒的症状。这些结果证实,细辛叶番薯的震颤性化合物或其有毒代谢产物会通过乳汁排出,并可使哺乳羔羊中毒。