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[溃疡坏死性小肠结肠炎:巨细胞病毒的作用。附病例报告]

[Ulcero-necrotizing enterocolitis: the role of cytomegalovirus. Apropos of a case].

作者信息

Fournier V, Gallet S, Rebaud P, Bouvier R, Dutruge J

机构信息

Clinique médicale infantile A, Centre Hospitalier Lyon-Sud, France.

出版信息

Pediatrie. 1989;44(3):189-92.

PMID:2544851
Abstract

The authors report a case of Wilson-Mikity syndrome in a preterm newborn, that was followed on the 28th day of life by a necrotizing enterocolitis with colic stenosis. The finding of cytomegalic cells on the pathologic examination of the intestinal lesions, the presence of the virus on direct examination of a tissue sample, the elevated IgG levels and the presence of IgM demonstrated a cytomegalovirus infection. The authors discuss the role of this virus in the pathogenesis of the affection, either as directly responsible for the enterocolitis or as a secondary colonization of previous lesions.

摘要

作者报告了一例早产新生儿的威尔逊-米基蒂综合征,该患儿在出生后第28天出现坏死性小肠结肠炎并伴有结肠狭窄。在肠道病变的病理检查中发现巨细胞,在组织样本直接检查中发现病毒,IgG水平升高以及IgM的存在表明存在巨细胞病毒感染。作者讨论了该病毒在疾病发病机制中的作用,是直接导致小肠结肠炎还是作为先前病变的继发性定植。

引用本文的文献

1
Congenital cytomegalovirus infection after recurrent infection: case reports and review of the literature.
Eur J Pediatr. 2003 Apr;162(4):248-53. doi: 10.1007/s00431-002-1115-5. Epub 2003 Feb 13.
2
Cytomegalovirus enteritis in a premature infant.
J Pediatr Surg. 1997 Nov;32(11):1545-7. doi: 10.1016/s0022-3468(97)90448-6.

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