欧洲荆豆凝集素1对犬肝细胞癌和胆管癌的凝集素组织化学染色
Ulex europaeus agglutinin 1 lectin histochemical staining of dog hepatocellular and bile duct carcinomas.
作者信息
Brown P J, Stephenson T J
机构信息
Department of Pathology, University of Bristol School of Veterinary Science, Langford.
出版信息
Res Vet Sci. 1989 May;46(3):421-3.
Ulex europaeus agglutinin 1 (UEA-1) lectin-binding is a feature of canine intrahepatic bile duct epithelial cells but not of canine hepatocytes. In tumours diagnosed histologically as cholangiocarcinomas or hepatocellular carcinomas, UEA-1 staining occurred in tumour cells regardless of histological appearance. The division of primary liver carcinomas into different presumed cell types of origin is not reflected by equivalent differentiation of the tumour cells and is not of diagnostic value.
欧洲荆豆凝集素1（UEA - 1）凝集素结合是犬肝内胆管上皮细胞的一个特征，而犬肝细胞则没有此特征。在组织学诊断为胆管癌或肝细胞癌的肿瘤中，无论组织学表现如何，肿瘤细胞中均出现UEA - 1染色。原发性肝癌分为不同假定细胞起源类型，但肿瘤细胞的等效分化并未体现这一点，且无诊断价值。
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