Wigley James, Shantikumar Saran, Hameed Waseem, Griffin Kathryn, Handa Ashok, Scott D Julian A
Department of Surgery, University Hospital Southampton, Southampton, UK.
Nuffield Department of Surgical Sciences, John Radcliffe Hospital, Oxford, UK; Division of Health Sciences, University of Warwick Medical School, Coventry, UK.
Ann Vasc Surg. 2015 Feb;29(2):385-91. doi: 10.1016/j.avsg.2014.10.007. Epub 2014 Oct 30.
Endovascular aortic aneurysm repair (EVAR) has been associated with a reduction in early morbidity and mortality compared with open surgery, creating an opportunity for aneurysm repair in those previously considered unfit for intervention. We determine the published incidence of complications and survival after elective EVAR in nonagenarians.
A systematic literature search was performed using the PubMed, EMBASE, and Cochrane databases up to December 2012. Two observers independently screened search results and extracted data.
Six retrospective reports were identified including 361 patients (81% men) with a mean age of 91.6 years. The mean aneurysm size was 69 mm. Comorbidities include hypertension (81%), ischemic heart disease (50%), peripheral vascular disease (30%), and chronic obstructive pulmonary disease (20%). There was no intraoperative mortality, 22% of patients had perioperative medical or surgical complications, and 24% had endoleaks. Mean duration of hospital stay was 4 days. Thirty-day mortality was 5%, and survival at 1, 3, and 5 years was 82%, 56%, and 17%, respectively.
Although the complication rates and longer term survival after elective EVAR in carefully selected nonagenarians appear acceptable, they are higher than those reported in younger patients. Given the typical life expectancy, careful consideration should be given to individual cases before undertaking EVAR in the nonagenarian.
与开放手术相比,血管内主动脉瘤修复术(EVAR)已使早期发病率和死亡率有所降低,这为那些先前被认为不适合干预的患者创造了动脉瘤修复的机会。我们确定了已发表的关于非agenarian(九十多岁老人)择期EVAR术后并发症发生率和生存率的数据。
截至2012年12月,使用PubMed、EMBASE和Cochrane数据库进行了系统的文献检索。两名观察者独立筛选检索结果并提取数据。
确定了6篇回顾性报告,包括361例患者(81%为男性),平均年龄91.6岁。动脉瘤平均大小为69毫米。合并症包括高血压(81%)、缺血性心脏病(50%)、外周血管疾病(30%)和慢性阻塞性肺疾病(20%)。无术中死亡,22%的患者有围手术期内科或外科并发症,24%有内漏。平均住院时间为4天。30天死亡率为5%,1年、3年和5年生存率分别为82%、56%和17%。
尽管在经过精心挑选的非agenarian患者中,择期EVAR术后的并发症发生率和长期生存率似乎可以接受,但高于年轻患者报告的数据。考虑到典型的预期寿命,在对非agenarian患者进行EVAR手术之前,应仔细考虑个体情况。