Dimou Francesca, Velanovich Vic
Division of General Surgery, University of South Florida, One Tampa General Circle, F145, Tampa, FL, 33606, USA.
J Gastrointest Surg. 2015 Feb;19(2):400-6. doi: 10.1007/s11605-014-2702-2. Epub 2014 Dec 2.
Esophageal and gastroduodenal perforations are relatively uncommon; however, they both can be potentially life-threatening. Esophageal perforations most commonly occur due to iatrogenic injury, forceful retching (Boerhaave's syndrome), malignancy, foreign body ingestion, or caustic injury. Gastroduodenal perforations are most commonly due to peptic ulcer disease or malignancy. Pain and signs of sepsis are the most common presenting symptoms and signs.
Determining the extent of critical illness and addressing hemodynamics and sepsis are the first priorities. Identifying the location and size of the perforation as well as extent of contamination is the next priorities. Although surgical intervention has been the mainstay of treatment, newer approaches have led to a heterogeneity of approaches.
For esophageal perforation, observation, endoscopic, radiological, and surgical approaches may be appropriate. For gastroduodenal perforation, surgical approach is still the most appropriate, although a concomitant acid-reducing operation is usually not necessary. Despite these advances, mortality for both perforations can still be high. Sound judgment is necessary for optimal results.
食管和胃十二指肠穿孔相对少见;然而,它们都可能危及生命。食管穿孔最常见的原因是医源性损伤、剧烈干呕(博赫哈夫综合征)、恶性肿瘤、异物吞食或腐蚀性损伤。胃十二指肠穿孔最常见的原因是消化性溃疡病或恶性肿瘤。疼痛和脓毒症迹象是最常见的症状和体征。
确定危重病程度并处理血流动力学和脓毒症是首要任务。确定穿孔的位置和大小以及污染程度是接下来的任务。尽管手术干预一直是主要治疗方法,但新方法导致了治疗方法的异质性。
对于食管穿孔,观察、内镜、放射学和手术方法可能适用。对于胃十二指肠穿孔,手术方法仍然是最合适的,尽管通常不需要同时进行减酸手术。尽管有这些进展,两种穿孔的死亡率仍然可能很高。为获得最佳结果,需要明智的判断。