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玉米抑制子-突变体转座元件的突变、表观突变及发育编程

Mutations, epimutations, and the developmental programming of the maize Suppressor-mutator transposable element.

作者信息

Fedoroff N, Masson P, Banks J A

出版信息

Bioessays. 1989 May;10(5):139-44. doi: 10.1002/bies.950100502.

DOI:10.1002/bies.950100502
PMID:2545188
Abstract

Information about the structure, function and regulation of the maize Suppressor-mutator (Spm) transposable element has emerged from the genetic and molecular characterization of both deletion mutations and an unconventional type of reversible genetic change (epimutation). The element is subject to an epigenetic mechanism that can either stably inactivate it or specify one of a variety of heritable programs of differential element expression in development. The essay explores the relationship between the Spm element's epigenetic developmental programming mechanism and the determinative events central to plant development and differentiation.

摘要

关于玉米抑制突变体(Spm)转座元件的结构、功能及调控的信息,来自对缺失突变以及一种非常规类型的可逆遗传变化(表观突变)的遗传和分子特征分析。该元件受一种表观遗传机制的影响,这种机制既能使其稳定失活,也能在发育过程中指定多种不同元件表达的可遗传程序中的一种。本文探讨了Spm元件的表观遗传发育编程机制与植物发育和分化核心的决定性事件之间的关系。

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1
Mutations, epimutations, and the developmental programming of the maize Suppressor-mutator transposable element.玉米抑制子-突变体转座元件的突变、表观突变及发育编程
Bioessays. 1989 May;10(5):139-44. doi: 10.1002/bies.950100502.
2
Epigenetic regulation of the maize Spm transposon.玉米Spm转座子的表观遗传调控
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Molecular mechanisms in the developmental regulation of the maize Suppressor-mutator transposable element.玉米抑制子-突变体转座元件发育调控中的分子机制。
Genes Dev. 1988 Nov;2(11):1364-80. doi: 10.1101/gad.2.11.1364.
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Mobility of the maize suppressor-mutator element in transgenic tobacco cells.玉米抑制-突变因子在转基因烟草细胞中的移动性。
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Is the Suppressor-mutator element controlled by a basic developmental regulatory mechanism?抑制突变元件是否受基本发育调控机制的控制?
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Genetic and molecular analysis of the Spm-dependent a-m2 alleles of the maize a locus.玉米a基因座中依赖Spm的α-m2等位基因的遗传与分子分析。
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Analysis of maize brittle-1 alleles and a defective Suppressor-mutator-induced mutable allele.玉米脆-1等位基因及一个缺陷型抑制子-突变体诱导的可变等位基因的分析
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TnpA trans-activates methylated maize Suppressor-mutator transposable elements in transgenic tobacco.TnpA在转基因烟草中反式激活甲基化的玉米抑制子-突变体转座元件。
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Maize Spm transposable element has an enhancer-insensitive promoter.玉米Spm转座元件具有一个对增强子不敏感的启动子。
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Mobility of the maize transposable element En/Spm in Arabidopsis thaliana.玉米转座因子En/Spm在拟南芥中的移动性。
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Rejuvenation by shoot apex culture recapitulates the developmental increase of methylation at the maize gene Pl-Blotched.
通过茎尖培养实现的幼化重现了玉米基因Pl-Blotched甲基化的发育性增加。
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DNaseI-sensitive and undermethylated rDNA is preferentially expressed in a maize hybrid.对脱氧核糖核酸酶I敏感且甲基化不足的核糖体DNA在玉米杂交种中优先表达。
Plant Mol Biol. 1993 Mar;21(5):805-21. doi: 10.1007/BF00027113.
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Differential inactivation and methylation of a transgene in plants by two suppressor loci containing homologous sequences.通过两个含有同源序列的抑制基因座实现植物中转基因的差异失活和甲基化。
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