Cavicchioli Paola, Valerio Enrico, Cutrone Mario
Department of Pediatrics, Ospedale Dell'Angelo, Mestre, Venice, Italy.
Department of Woman and Child Health, Medical School, University of Padova, Padova, Italy.
AJP Rep. 2014 Nov;4(2):e81-2. doi: 10.1055/s-0034-1383853. Epub 2014 Aug 11.
Case Report Two female monochorionic-monoamniotic twins showed the same kind of infantile perineal protrusion (IPP) at birth. Lesions in both twins progressively healed until resolution in 6 weeks' time; none of the twins have manifested, till date, alvus disturbances. Discussion and Literature Review A literature review numbers approximately 100 reports of IPP. This condition has been classically classified into three categories: congenital/familiar (i.e., female sex, positive parental history of IPP), acquired (mainly due to constipation), and associated with lichen sclerosus et atrophicus. Conclusions and Final Remarks This case report describes, for the first time, the presence of IPP in monochorionic-monoamniotic twins, supporting the existence of hereditary/genetic factors in the developing of this condition.
两名单绒毛膜单羊膜囊双胎女婴出生时出现同一种婴儿会阴突出（IPP）。两个双胎儿的病变逐渐愈合，直至6周时消退；迄今为止，两个双胎儿均未出现肠道功能紊乱。讨论与文献综述：文献综述约有100篇关于IPP的报道。这种情况传统上分为三类：先天性/家族性（即女性、有IPP阳性家族史）、后天性（主要由于便秘）以及与硬化性萎缩性苔藓相关。结论与结束语：本病例报告首次描述了单绒毛膜单羊膜囊双胎中存在IPP，支持了这种情况发生过程中存在遗传/基因因素。
