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急性心肌梗死住院后28天和1年死亡率的教育不平等——一项全国性队列研究

Educational inequalities in 28 day and 1-year mortality after hospitalisation for incident acute myocardial infarction--a nationwide cohort study.

作者信息

Igland Jannicke, Vollset Stein Emil, Nygård Ottar K, Sulo Gerhard, Sulo Enxhela, Ebbing Marta, Næss Øyvind, Ariansen Inger, Tell Grethe S

机构信息

Department of Global Public Health and Primary Care, University of Bergen, PB 7804, 5018 Bergen, Norway.

Department of Global Public Health and Primary Care, University of Bergen, PB 7804, 5018 Bergen, Norway; Department of Health Registries, Norwegian Institute of Public Health, Kalfarveien 31, 5018 Bergen, Norway.

出版信息

Int J Cardiol. 2014 Dec 20;177(3):874-80. doi: 10.1016/j.ijcard.2014.10.045. Epub 2014 Oct 28.

Abstract

BACKGROUND

There is little recent evidence on the impact of comorbidities and access to revascularisation procedures on educational inequalities in mortality after acute myocardial infarction (AMI). The aim of the study was to investigate educational inequalities in mortality among all patients hospitalised for an incident AMI during 2001-2009 in Norway.

METHODS

Data were obtained through the Cardiovascular Disease in Norway (CVDNOR) project. Incident AMI was defined as an AMI-hospitalisation without any AMI-events in the previous 7 years. Education was categorised as basic, upper secondary or tertiary (college/university). Cox regression was used to assess educational differences in 28-day and 29-365-day mortality after an incident AMI in terms of hazard ratios and relative index of inequality (RII). RII can be interpreted as the ratio in mortality between the 0 th and the 100th percentile of the education distribution.

RESULTS

111 993 incident AMIs were included (39.4% women). Among patients aged 35-69, RIIs (95% CI) adjusted for age, sex and year were 1.86 (1.59-2.18) and 2.10 (1.69-2.59) for 28-day and 29-365-day mortality respectively. Among patients aged 70-94 the corresponding RIIs were 1.12 (1.06-1.30) and 1.28 (1.19-1.38). Educational inequalities in mortality were attenuated after adjustment for comorbidities and revascularisation, but were still significant. Educational inequalities did not decrease during 2001-2009.

CONCLUSION

Educational inequalities in both 28-day and 29-365 day mortality were strong and persistent during 2001-2009. Further research is needed to investigate if these disparities are driven by inequalities in the severity of the AMI or by inequitable access to treatment and rehabilitation.

摘要

背景

近期关于合并症及血管重建手术可及性对急性心肌梗死(AMI)后死亡率教育不平等影响的证据较少。本研究旨在调查2001年至2009年期间挪威所有因首次AMI住院患者的死亡率教育不平等情况。

方法

数据通过挪威心血管疾病(CVDNOR)项目获得。首次AMI定义为在过去7年中无任何AMI事件的AMI住院。教育程度分为基础、高中或高等教育(学院/大学)。采用Cox回归,根据风险比和不平等相对指数(RII)评估首次AMI后28天和29至365天死亡率的教育差异。RII可解释为教育分布第0百分位数与第100百分位数之间的死亡率比值。

结果

纳入111993例首次AMI患者(39.4%为女性)。在35至69岁患者中,经年龄、性别和年份调整后的RII(95%CI),28天死亡率为1.86(1.59至2.18),29至365天死亡率为2.10(1.69至2.59)。在70至94岁患者中,相应的RII分别为1.12(1.06至1.30)和1.28(1.19至1.38)。调整合并症和血管重建后,死亡率的教育不平等有所减弱,但仍很显著。2001年至2009年期间,教育不平等并未减少。

结论

2001年至2009年期间,28天和29至365天死亡率的教育不平等都很严重且持续存在。需要进一步研究以调查这些差异是由AMI严重程度的不平等还是治疗和康复的不公平可及性所驱动。

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