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青少年 HPV 疫苗接种的适应证:文献复习。

Indications for the HPV vaccine in adolescents: a review of the literature.

机构信息

Oral Oncology Center, Department of Pathology and Clinical Propaedeutics, Araçatuba School of Dentistry, UNESP - Univ Estadual Paulista, Araçatuba, SP, Brazil.

Department of Dental Materials and Prosthodontics, Araçatuba School of Dentistry, UNESP - Univ Estadual Paulista, Araçatuba, SP, Brazil.

出版信息

J Infect Public Health. 2015 Mar-Apr;8(2):105-16. doi: 10.1016/j.jiph.2014.08.011. Epub 2014 Oct 13.

Abstract

BACKGROUND

The vaccine against human papillomavirus (HPV) was created to abrogate the risk that the virus presents for the development of cervical cancers. The prevalence of HPV infection among healthy individuals is significant (20%). We performed a review of the literature published in the period from 2008 to 2012 regarding the use of the vaccine against HPV specifically in adolescents.

METHODS

The articles were selected from a search of the PubMed database with the key words "vaccine", "HPV" and "adolescent". This search identified 576 articles; based on readings of the titles and abstracts, the list of included article was reduced to 42.

RESULTS

We observed that the majority of authors are in favor of the vaccine for adolescents particularly females.

CONCLUSION

Recommending the use of the HPV vaccine and other vaccines represents an attempt to broaden the reach of these vaccines among both sexes of the adolescent population. Vaccination is a strategy for the prevention of pre-cancerous lesions in the genital and oropharyngeal regions.

摘要

背景

人乳头瘤病毒(HPV)疫苗的研发旨在消除 HPV 病毒对宫颈癌发展的风险。在健康人群中,HPV 感染的流行率相当高(20%)。我们对 2008 年至 2012 年期间发表的关于 HPV 疫苗在青少年中的具体使用的文献进行了综述。

方法

我们从 PubMed 数据库中使用“疫苗”、“HPV”和“青少年”等关键词进行了检索。该搜索共识别出 576 篇文章;根据标题和摘要的阅读,将纳入文章的列表减少到 42 篇。

结果

我们观察到大多数作者都赞成青少年,尤其是女性接种疫苗。

结论

推荐 HPV 疫苗和其他疫苗的使用,代表了扩大这些疫苗在青少年两性人群中普及度的尝试。疫苗接种是预防生殖器和口咽区域癌前病变的一种策略。

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