Department of Dermatology, Robert Wood Johnson Medical School, Rutgers University, New Brunswick, New Jersey.
Department of Dermatology, Robert Wood Johnson Medical School, Rutgers University, New Brunswick, New Jersey.
J Am Acad Dermatol. 2014 Dec;71(6):1039.e1-1039.e12. doi: 10.1016/j.jaad.2014.06.015. Epub 2014 Nov 15.
Patients commonly inquire about dietary modifications as a means to prevent or manage skin disease. Answering these questions is often challenging, given the vast and conflicting evidence that exists on this topic. This 2-part continuing medical education article summarizes the evidence to date to enable physicians to answer patients' questions in an evidence-based manner. Part I includes atopic dermatitis, acne, and nonmelanoma skin cancer. The role of dietary supplementation, dietary exclusion, food allergy, maternal diet, and breastfeeding in the development and/or prevention of atopic dermatitis is summarized. The dermatoendocrinologic mechanism for the effects of glycemic index/glycemic load and milk on acne is described, as well as related clinical evidence for dietary modifications. Finally, evidence and recommendations for restriction or supplementation of dietary factors in the prevention of nonmelanoma skin cancer, including fat, vitamins A, C, D, and E, and selenium, are reported.
患者常询问饮食调整是否可预防或治疗皮肤病。鉴于该主题存在大量相互矛盾的证据，回答这些问题常常颇具挑战。本继续教育系列文章共 2 部分，旨在总结现有证据，使医生能够循证解答患者的问题。第 1 部分包括特应性皮炎、痤疮和非黑素瘤性皮肤癌。本文总结了饮食补充、饮食排除、食物过敏、母体饮食和母乳喂养在特应性皮炎发病和/或预防中的作用。文中还描述了血糖指数/血糖负荷和牛奶影响痤疮的皮肤内分泌机制，以及相关的饮食调整临床证据。最后，报告了限制或补充非黑素瘤性皮肤癌相关饮食因素（包括脂肪、维生素 A、C、D、E 和硒）的证据和建议。
