Dua Anahita, Desai Sapan S, Seabrook Gary R, Brown Kellie R, Lewis Brian D, Rossi Peter J, Edmiston Charles E, Lee Cheong J
Division of Vascular Surgery, Department of Surgery, Medical College of Wisconsin, Milwaukee, Wisc.
Department of Vascular Surgery, Southern Illinois University, Springfield, Ill.
J Vasc Surg. 2014 Dec;60(6):1635-9. doi: 10.1016/j.jvs.2014.08.072. Epub 2014 Nov 21.
The Surgical Care Improvement Project (SCIP) is a national initiative to reduce surgical complications, including postoperative surgical site infection (SSI), through protocol-driven antibiotic usage. This study aimed to determine the effect SCIP guidelines have had on in-hospital SSIs after open vascular procedures.
The Nationwide Inpatient Sample (NIS) was retrospectively analyzed using International Classification of Diseases, Ninth Revision, diagnosis codes to capture SSIs in hospital patients who underwent elective carotid endarterectomy, elective open repair of an abdominal aortic aneurysm (AAA), and peripheral bypass. The pre-SCIP era was defined as 2000 to 2005 and post-SCIP was defined as 2007 to 2010. The year 2006 was excluded because this was the transition year in which the SCIP guidelines were implemented. Analysis of variance and χ(2) testing were used for statistical analysis.
The rate of SSI in the pre-SCIP era was 2.2% compared with 2.3% for carotid endarterectomy (P = .06). For peripheral bypass, both in the pre- and post-SCIP era, infection rates were 0.1% (P = .22). For open, elective AAA, the rate of infection in the post-SCIP era increased significantly to 1.4% from 1.0% in the pre-SCIP era (P < .001). Demographics and in-hospital mortality did not differ significantly between the groups.
Implementation of SCIP guidelines has made no significant effect on the incidence of in-hospital SSIs in open vascular operations; rather, an increase in SSI rates in open AAA repairs was observed. Patient-centered, bundled approaches to care, rather than current SCIP practices, may further decrease SSI rates in vascular patients undergoing open procedures.
外科护理改进项目(SCIP)是一项全国性倡议,旨在通过规范抗生素使用来减少手术并发症,包括术后手术部位感染(SSI)。本研究旨在确定SCIP指南对开放性血管手术后院内SSI的影响。
使用国际疾病分类第九版诊断编码对全国住院患者样本(NIS)进行回顾性分析,以获取接受择期颈动脉内膜切除术、择期腹主动脉瘤(AAA)开放性修复术和外周血管搭桥术的住院患者的SSI情况。SCIP实施前的时期定义为2000年至2005年,SCIP实施后的时期定义为2007年至2010年。2006年被排除,因为这是SCIP指南实施的过渡年。采用方差分析和χ²检验进行统计分析。
SCIP实施前时期的SSI发生率为2.2%,颈动脉内膜切除术的SSI发生率为2.3%(P = 0.06)。对于外周血管搭桥术,SCIP实施前后的感染率均为0.1%(P = 0.22)。对于开放性择期AAA,SCIP实施后时期的感染率从SCIP实施前时期的1.0%显著增加至1.4%(P < 0.001)。各组之间的人口统计学特征和院内死亡率无显著差异。
SCIP指南的实施对开放性血管手术中院内SSI的发生率没有显著影响;相反,观察到开放性AAA修复术中SSI发生率有所增加。以患者为中心的综合护理方法,而非当前的SCIP做法,可能会进一步降低接受开放性手术的血管疾病患者的SSI发生率。