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钩叶黄酮A-F,从中华卷柏(Desv.)Spring中分离得到的六种新型黄酮类化合物。

Unciflavones A-F, six novel flavonoids from Selaginella uncinata (Desv.) Spring.

作者信息

Zou Hui, Xu Kang-Ping, Li Fu-Shuang, Zou Zhen-Xing, Liu Rui, Liu Rui-Huan, Li Jing, Tan Lei-Hong, Tan Gui-Shan

机构信息

School of Pharmaceutical Sciences, Central South University, Changsha 410013, PR China; Department of Pharmaceutical Science, Medical College of Hunan Normal University, Changsha, Hunan 410013, PR China.

School of Pharmaceutical Sciences, Central South University, Changsha 410013, PR China.

出版信息

Fitoterapia. 2014 Dec;99:328-33. doi: 10.1016/j.fitote.2014.10.012. Epub 2014 Oct 22.

Abstract

Six new flavonoids, unciflavones A-F (1-6), have been isolated from medicinal plant Selaginella uncinata (Desv.) Spring. Their structures were established on the basis of extensive NMR analysis including 1D NMR ((1)H, (13)C and DEPT) and 2D NMR (COSY, HSQC, HMBC) experiments as well as HRESIMS analysis. All compounds possess exceptional structural features with an aryl substituent at the C-8 position, which are uncommonly encountered in natural resources and firstly reported in genus Selaginella.

摘要

从药用植物中华卷柏(Selaginella uncinata (Desv.) Spring)中分离出了六种新黄酮类化合物,即卷柏黄酮A - F(1 - 6)。它们的结构是在广泛的核磁共振分析基础上确定的,包括一维核磁共振(¹H、¹³C和DEPT)和二维核磁共振(COSY、HSQC、HMBC)实验以及高分辨电喷雾电离质谱分析。所有化合物都具有独特的结构特征,在C - 8位有一个芳基取代基,这在天然资源中并不常见,并且首次在卷柏属中报道。

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