Four new biflavonoids from Selaginella uncinata and their anti-anoxic effect.
作者信息
Zheng Jun-Xia, Wang Nai-Li, Liu Hong-Wei, Chen Hai-Feng, Li Ming-Ming, Wu Li-Ying, Fan Ming, Yao Xin-Sheng
机构信息
School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang, China.
出版信息
J Asian Nat Prod Res. 2008 Sep-Oct;10(9-10):945-52. doi: 10.1080/10286020802181166.
The 60% ethanolic extract of Selaginella uncinata (Desv.) Spring possessed potent anti-anoxic effect in the anoxic PC12 cell assay. A phytochemical study of its EtOAc-soluble part led to the isolation of four new and three known biflavonoids. Their structures were established on the basis of physico-chemical properties and spectroscopic analysis. The absolute configurations of the new compounds were determined with the aid of circular dichroism (CD) spectroscopy. Compounds 4 and 5 showed potent anti-anoxic effect in the anoxic PC12 cell assay.
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