通过磁性激活细胞分选（MACS）筛选的不育男性精子的形态学评估。
Morphological evaluation of sperm from infertile men selected by magnetic activated cell sorting (MACS).
作者信息
Curti Gianni, Skowronek Fernanda, Vernochi Rita, Rodriguez-Buzzi Ana Laura, Rodriguez-Buzzi Juan Carlos, Casanova Gabriela, Sapiro Rossana
机构信息
Departamento de Biologia Molecular - Instituto De Investigaciones Biológicas Clemente Estable (IIBCE), Avenida Italia 3318, CP 11600 Montevideo, Uruguay.
Laboratorio de Biología Molecular de la Reproducción - Departamento de Histología y Embriología, Facultad de Medicina, Gral. Flores 2125, 11800 Montevideo, Uruguay.
出版信息
Reprod Biol. 2014 Dec;14(4):289-92. doi: 10.1016/j.repbio.2014.07.002. Epub 2014 Aug 8.
Electron microscopy analysis performed in five infertile human subjects after sperm selection by swim-up followed by magnetic activated cell sorting (MACS) demonstrated a decrease in the number of spermatozoa with characteristics compatible with cell death. However, no significant differences were found when the swim-up/MACS semen fraction was compared with swim-up fraction alone.
对五名不育男性受试者的精液样本进行分析，样本经上游法筛选精子后再进行磁珠分选（MACS），随后进行电子显微镜分析，结果显示具有细胞死亡特征的精子数量减少。然而，将上游法/磁珠分选后的精液部分与仅采用上游法的部分进行比较时，未发现显著差异。
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