Desai M J, Nava A, Rigoard P, Shah B, Taylor R S
International Spine, Pain & Performance Center, Washington DC, USA.
International Spine, Pain & Performance Center, Washington DC, USA.
Neurochirurgie. 2015 Mar;61 Suppl 1:S66-76. doi: 10.1016/j.neuchi.2014.09.002. Epub 2014 Nov 22.
Failed back surgery syndrome (FBSS) constitutes a constellation of symptoms grouped together and attributed to prior surgical intervention. Clinicians often poorly understand the heterogeneity of this condition combined with the etiological factors responsible for its development. Therefore, it would follow that an algorithmic treatment approach to patients diagnosed with this syndrome might pose challenges. The clinical work-up of the patient involves history, examination and appropriate diagnostic imaging as well as behavioral assessment.
We sought to conduct a narrative review of the available literature focused on the medical, rehabilitative and behavioral treatment of FBSS. To that end, we conducted a literature search using PubMed (through March 2013). We focused on studies published over the last 20years. Only English language articles were included. Search terms included "failed back surgery syndrome", "FBSS", "failed back syndrome", and "post-laminectomy syndrome". Studies included in our review focused on randomized controlled trials (RCTs), prospective cohort studies, and case series (retrospective and prospective). Studies were organized by intervention (e.g. medical management, physical therapy and rehabilitation, and psychosocial) and presented to emphasize the quality of evidence (e.g. RCTs, prospective studies, etc.).
Overall, the literature provides very limited guidance on the comprehensive management of patients suffering from FBSS. There are rehabilitative interventions and behavioral protocols that demonstrate promise. Pathways based on medication management remain difficult to clearly define.
腰椎手术失败综合征(FBSS)是一组因先前手术干预而出现的症状群。临床医生往往对该病症的异质性以及导致其发生的病因了解不足。因此,对于诊断为此综合征的患者采用算法式治疗方法可能会面临挑战。对患者的临床检查包括病史、体格检查、适当的诊断性影像学检查以及行为评估。
我们试图对现有文献进行叙述性综述,重点关注FBSS的医学、康复和行为治疗。为此,我们使用PubMed(截至2013年3月)进行文献检索。我们聚焦于过去20年发表的研究。仅纳入英文文章。检索词包括“腰椎手术失败综合征”“FBSS”“腰椎手术失败综合征”和“椎板切除术后综合征”。我们综述中纳入的研究聚焦于随机对照试验(RCT)、前瞻性队列研究和病例系列(回顾性和前瞻性)。研究按干预措施(如药物治疗、物理治疗与康复以及心理社会干预)进行组织,并着重展示证据质量(如RCT、前瞻性研究等)。
总体而言,文献对于FBSS患者的综合管理提供的指导非常有限。有一些康复干预措施和行为方案显示出前景。基于药物治疗的途径仍难以明确界定。