• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

相似文献

1
Nitrous oxide for pain management of first trimester surgical abortion -- a randomized controlled pilot study.一氧化二氮用于孕早期人工流产手术的疼痛管理——一项随机对照试验性研究
Contraception. 2015 Feb;91(2):164-6. doi: 10.1016/j.contraception.2014.09.013. Epub 2014 Oct 22.
2
Nitrous oxide versus oral sedation for pain management of first-trimester surgical abortion - a randomized study.一氧化二氮与口服镇静用于孕早期人工流产镇痛的随机研究
Contraception. 2017 Aug;96(2):118-123. doi: 10.1016/j.contraception.2017.06.003. Epub 2017 Jun 16.
3
Nitrous Oxide Compared With Intravenous Sedation for Second-Trimester Abortion: A Randomized Controlled Trial.笑气与静脉镇静用于中期妊娠流产的比较：一项随机对照试验。
Obstet Gynecol. 2018 Nov;132(5):1192-1197. doi: 10.1097/AOG.0000000000002915.
4
Intramuscular ketorolac versus oral ibuprofen for pain relief in first-trimester surgical abortion: a randomized clinical trial.肌内注射酮咯酸与口服布洛芬用于缓解早期妊娠手术流产疼痛：一项随机临床试验。
Contraception. 2014 Feb;89(2):116-21. doi: 10.1016/j.contraception.2013.10.009. Epub 2013 Oct 26.
5
Pre-emptive effect of ibuprofen versus placebo on pain relief and success rates of medical abortion: a double-blind, randomized, controlled study.布洛芬与安慰剂对药物流产止痛效果和成功率的预先作用：一项双盲、随机、对照研究。
Fertil Steril. 2012 Mar;97(3):612-5. doi: 10.1016/j.fertnstert.2011.12.041. Epub 2012 Jan 20.
6
Paracervical block as pain treatment during second-trimester medical termination of pregnancy: an RCT with bupivacaine versus sodium chloride.宫颈旁阻滞用于孕中期药物流产时的疼痛治疗：布比卡因与氯化钠对比的随机对照试验
Hum Reprod. 2016 Jan;31(1):67-74. doi: 10.1093/humrep/dev286. Epub 2015 Nov 15.
7
Music as an auxiliary analgesic during first trimester surgical abortion: a randomized controlled trial.音乐在第一孕期手术流产中作为辅助镇痛剂的随机对照试验。
Contraception. 2012 Aug;86(2):157-62. doi: 10.1016/j.contraception.2011.11.017. Epub 2012 Jan 10.
8
Nitrous oxide for pain management during in-office hysteroscopic sterilization: a randomized controlled trial.笑气用于门诊宫腔镜绝育术中的疼痛管理：一项随机对照试验。
Contraception. 2017 Mar;95(3):239-244. doi: 10.1016/j.contraception.2016.09.006. Epub 2016 Sep 9.
9
An Evaluation of Oral Midazolam for Anxiety and Pain in First-Trimester Surgical Abortion: A Randomized Controlled Trial.孕早期手术流产中口服咪达唑仑治疗焦虑和疼痛的评估：一项随机对照试验
Obstet Gynecol. 2015 Jul;126(1):37-46. doi: 10.1097/AOG.0000000000000913.
10
A fixed nitrous oxide/oxygen mixture as an analgesic for trauma patients in emergency department: study protocol for a randomized, controlled trial.固定浓度氧化亚氮/氧气混合气体作为急诊科创伤患者的镇痛剂：一项随机对照试验的研究方案。
Trials. 2018 Sep 29;19(1):527. doi: 10.1186/s13063-018-2899-6.

引用本文的文献

1
Local anaesthesia for pain control in first trimester surgical abortion.在妊娠早期手术流产中进行局部麻醉以控制疼痛。
Cochrane Database Syst Rev. 2024 Feb 13;2(2):CD006712. doi: 10.1002/14651858.CD006712.pub3.
2
Comparison of analgesic and anxiolytic effects of nitrous oxide in burn wound treatment: A single-blind prospective randomized controlled trial.一氧化二氮在烧伤创面治疗中的镇痛和抗焦虑作用比较：一项单盲前瞻性随机对照试验。
Medicine (Baltimore). 2019 Dec;98(51):e18188. doi: 10.1097/MD.0000000000018188.
3
Nitrous oxide versus oral sedation for pain management of first-trimester surgical abortion - a randomized study.一氧化二氮与口服镇静用于孕早期人工流产镇痛的随机研究
Contraception. 2017 Aug;96(2):118-123. doi: 10.1016/j.contraception.2017.06.003. Epub 2017 Jun 16.

本文引用的文献

1
Paracervical block for pain control in first-trimester surgical abortion: a randomized controlled trial.经阴道宫颈旁阻滞在早孕手术流产中镇痛效果的随机对照研究。
Obstet Gynecol. 2012 May;119(5):1030-7. doi: 10.1097/AOG.0b013e318250b13e.
2
A double-blind, randomized controlled trial of the use of a 50:50 mixture of nitrous oxide/oxygen in legal abortions.一项关于在合法堕胎中使用 50:50 一氧化二氮/氧气混合物的双盲、随机对照试验。
Contraception. 2012 Jul;86(1):79-83. doi: 10.1016/j.contraception.2011.11.015. Epub 2012 Jan 20.
3
Women's preferences for pain control during first-trimester surgical abortion: a qualitative study.**妇女在孕早期手术流产中对疼痛控制的偏好：一项定性研究。**
Contraception. 2012 Apr;85(4):413-8. doi: 10.1016/j.contraception.2011.08.019. Epub 2011 Oct 11.
4
Pain control in first trimester surgical abortion.孕早期人工流产的疼痛控制
Cochrane Database Syst Rev. 2009 Apr 15;2009(2):CD006712. doi: 10.1002/14651858.CD006712.pub2.
5
First-trimester surgical abortion practices: a survey of National Abortion Federation members.孕早期手术流产操作：对美国国家堕胎联合会成员的一项调查
Contraception. 2009 May;79(5):385-92. doi: 10.1016/j.contraception.2008.11.005. Epub 2008 Dec 11.
6
Abortion in the United States: incidence and access to services, 2005.2005年美国的堕胎情况：发生率及服务可及性
Perspect Sex Reprod Health. 2008 Mar;40(1):6-16. doi: 10.1363/4000608.
7
A double-blind, randomized controlled trial on the use of a 50:50 mixture of nitrous oxide/oxygen in pain relief during suction evacuation for the first trimester pregnancy termination.
Hum Reprod. 2006 Oct;21(10):2606-11. doi: 10.1093/humrep/del234. Epub 2006 Jun 21.
8
Four percent intrauterine lidocaine infusion for pain management in first-trimester abortions.用于孕早期人工流产疼痛管理的4%宫腔内利多卡因输注
Obstet Gynecol. 2006 Feb;107(2 Pt 1):269-75. doi: 10.1097/01.AOG.0000194204.71925.4a.
9
The effects of nitrous oxide on responses evoked in the brain stem by tooth stimulation.氧化亚氮对牙齿刺激诱发的脑干反应的影响。
Anesthesiology. 1957 Mar-Apr;18(2):183-95. doi: 10.1097/00000542-195703000-00001.

一氧化二氮用于孕早期人工流产手术的疼痛管理——一项随机对照试验性研究

Nitrous oxide for pain management of first trimester surgical abortion -- a randomized controlled pilot study.

作者信息

Singh Rameet H, Espey Eve, Carr Shannon, Pereda Brenda, Ogburn Tony, Leeman Lawrence

机构信息

University of New Mexico School of Medicine Department of Obstetrics and Gynecology, Albuquerque, New Mexico.

University of New Mexico School of Medicine Department of Obstetrics and Gynecology, Albuquerque, New Mexico.

出版信息

Contraception. 2015 Feb;91(2):164-6. doi: 10.1016/j.contraception.2014.09.013. Epub 2014 Oct 22.

DOI:10.1016/j.contraception.2014.09.013
PMID:25459096
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5317271/
Abstract

OBJECTIVE

The objective was to determine feasibility of a study comparing mean pain scores between women randomized to nitrous oxide/oxygen (NO) versus oxygen+oral analgesics for trimester surgical abortion.

STUDY DESIGN

Pilot randomized controlled trial comparing NO (n=10) versus oxygen+oral analgesics (n=10). Feasibility of subject recruitment, and pain and satisfaction scores on a visual analog scale were evaluated.

RESULTS

Fifty-seven percent of eligible women participated. Mean pain scores were similar between groups, and mean satisfaction scores were higher for the NO group (77.5 vs. 46.7, P=.048).

CONCLUSIONS

The majority of eligible women agreed to participate in this study evaluating an uncommon pain control intervention.

摘要

目的

本研究旨在确定一项比较接受一氧化二氮/氧气（NO）与氧气加口服镇痛药的女性在孕中期人工流产时平均疼痛评分的研究的可行性。

研究设计

先导性随机对照试验，比较NO组（n = 10）和氧气加口服镇痛药组（n = 10）。评估了受试者招募的可行性，以及视觉模拟量表上的疼痛和满意度评分。

结果

57%符合条件的女性参与了研究。两组的平均疼痛评分相似，NO组的平均满意度评分更高（77.5对46.7，P = 0.048）。

结论

大多数符合条件的女性同意参与这项评估一种不常见疼痛控制干预措施的研究。