Huffaker Michelle Fox, Phipatanakul Wanda
Division of Medicine, Brigham and Women's Hospital, Harvard Medical School, 75 Francis Street, Boston, MA 02115, USA.
Division of Immunology, Boston Children's Hospital, Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115, USA.
Immunol Allergy Clin North Am. 2015 Feb;35(1):129-44. doi: 10.1016/j.iac.2014.09.005. Epub 2014 Nov 21.
Over the past several decades, the evidence supporting rational pediatric asthma management has grown considerably. As more is learned about the various phenotypes of asthma, the complexity of management will continue to grow. This article focuses on the evidence supporting the current guidelines-based pediatric asthma management and explores the future of asthma management with respect to phenotypic heterogeneity and biologics.
在过去几十年里，支持合理的儿童哮喘管理的证据大幅增加。随着对哮喘各种表型的了解越来越多，管理的复杂性将持续增加。本文重点关注支持当前基于指南的儿童哮喘管理的证据，并探讨哮喘管理在表型异质性和生物制剂方面的未来发展。
