Effective treatment of d-penicillamine induced elastosis perforans serpiginosa with ALA-PDT.
作者信息
Wang Duoqin, Liang Jun, Xu Jinhua, Chen Lianjun
机构信息
Fudan University, Huashan Hospital, Department of Dermatology, 12 Wulumuqi Zhong Road, Jing'an District, Shanghai 200040, People's Republic of China.
Fudan University, Huashan Hospital, Department of Dermatology, 12 Wulumuqi Zhong Road, Jing'an District, Shanghai 200040, People's Republic of China; District Central Hospital of Shanghai, Department of Dermatology, 256 Xikang Road, Jing'an District, Shanghai 200040, People's republic of China.
出版信息
Photodiagnosis Photodyn Ther. 2015 Mar;12(1):140-2. doi: 10.1016/j.pdpdt.2014.11.001. Epub 2014 Nov 22.
A case of D-penicillamine(DPA) induced elastosis perforans serpiginosa(EPS) in a 32-year-old Chinese man was reported. The presentation lasted two years and was refractory to traditional medical treatment. He was then commenced on 7.6% 5-aminolevulinic acid (ALA) induced photodynamic therapy(PDT) by a LED light of 633 nm at dose levels of 130J/ cm2 for each session with total 3 sessions at one week interval. The patient was tolerated and responded well to this new approach for DPA-induced EPS without any adverse events. The etiology, pathophysiology, natural history, and treatment options for DPA-induced EPS are reviewed, and the authors suggest this method of treatment to be effective and safe for patients of DPA-induced EPS refractory to conventional therapy.
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