Chisti Muzamil Amin, Binamer Yousef, Alfadley Abdullah, Almutawa Abdulmonem
Dr. Muzamil Amin Chisti, MBC 46 Department of Dermatology,, King Faisal Specialist Hospital and Research Centre,, PO Box 3354, Riyadh 11211, Saudi Arabia, T: +966114424608,
Ann Saudi Med. 2019 Jan-Feb;39(1):56-60. doi: 10.5144/0256-4947.2019.56.
D-penicillamine (DPA)-induced pseudo-pseudoxanthoma elasticum (PXE) and elastosis perforans serpiginosa (EPS) has been reported in the past, but most of the treatment modalities used before have a sub.optimal response. We report a case of DPA-induced pseudo-PXE with extensive EPS who had an excellent rapid response to acitretin. To the best of our knowledge no such report has been published in the past, even though there is a single report of effectiveness of isotretinoin in elastosis perforans serpiginosa. SIMILAR CASES PUBLISHED: One similar case but with a different medication (reference 13).
过去曾有报道称D-青霉胺（DPA）可诱发假性弹性假黄瘤（PXE）和匐行性穿通性弹力纤维病（EPS），但以往使用的大多数治疗方法反应欠佳。我们报告1例DPA诱发的伴有广泛EPS的假性PXE患者，其对阿维A治疗反应迅速且效果良好。据我们所知，尽管曾有1篇关于异维A酸治疗匐行性穿通性弹力纤维病有效性的报告，但过去未曾发表过此类报告。已发表的类似病例：1例类似病例，但用药不同（参考文献13）。
