Scheele J, Altendorf-Hofmann A, Stangl R, Groite H, Gall F P
Chirurgischen Klinik mit Poliklinik, Universität Erlangen--Nürnberg.
Zentralbl Chir. 1989;114(10):639-54.
From 1970 through 1986, a total of 62 patients underwent thoracotomy for colorectal metastases to the lungs. Four had exploration only, whereas in 13 a nonradical, and in 45 a "curative" resection was performed. There was one postoperative death. Cumulative 5-year survival following radical resection was 44%. Conversely, all other patients succumbed within 3 years. Extrapulmonary disease has not yet been associated with 5-year survival and may usually contraindicate resection. The impacts of multiple metastases exceeding 3 nodules or bilateral pulmonary involvement on prognosis can not been determined from our series, since the procedure in respective patients was not radical in the majority of cases. In turn, localisation and venous drainage of the primary tumor did not significantly influence long term survival.
从1970年到1986年，共有62例患者因结直肠癌肺转移接受了开胸手术。4例仅接受了探查，13例进行了非根治性切除，45例进行了“根治性”切除。术后有1例死亡。根治性切除后的5年累积生存率为44%。相反，所有其他患者在3年内死亡。肺外疾病与5年生存率尚无关联，通常可能提示不宜进行切除。由于大多数病例中相应患者的手术并非根治性的，因此我们的系列研究无法确定超过3个结节的多发转移或双侧肺受累对预后的影响。反过来，原发肿瘤的位置和静脉引流对长期生存没有显著影响。
