Sang Pei-ming, Zhang Ming, Chen Bin-hui, Cai Chang, Gu Shi-rong, Zhou Min
Zhongguo Gu Shang. 2014 Aug;27(8):654-7.
To explore the effects of nano-hydroxyapatite/polyamide 66 (n-HA/PA66) cage on recovering and maintaining lumbar curvature, lumbar heights and fusion rate when used in the transforaminal lumbar interbody fusion.
From February to July 2012, 50 patients with degenerative lumbar disease(lumbar disc herniation in 32 cases and lumbar spondylolisthesis in 18 cases) were treated with transforaminal lumbar interbody fusion using the n-HA/PA66 cage, and their preoperative and postoperative clinical outcomes were analyzed. The patients were followed up for 2, 4, 6 and 8 months after operation, during which the CR and CT film of lumbar vertebra were checked to get relative height of vertebral space, Taillard index,index of lumbar spinal curvature,angle of segmental and full lumbar lordosis. The data were analyzed respectively with pair t-test, analysis of variance or LSD-t-test.
All the patients were followed up, and the duraion ranged from 8 to 13 months, with a mean of 11.32 months. There were significant differences in relative height of vertebral space, Taillard index, index of lumbar spinal curvature, angle of segmental and full lumbar lordosis after surgery, but there were no significant differences in different periods after operation. The fusion time of lumbar ranged from 4 to 8 months.
The n-HA/PA66 cage can recover and maintain lumbar normal stability with higher rate of fusion and less complications.
探讨纳米羟基磷灰石/聚酰胺66（n-HA/PA66）椎间融合器在经椎间孔腰椎椎间融合术中对恢复和维持腰椎曲度、腰椎高度及融合率的影响。
2012年2月至7月，对50例退变性腰椎疾病患者（32例腰椎间盘突出症，18例腰椎滑脱症）采用n-HA/PA66椎间融合器行经椎间孔腰椎椎间融合术，并分析其术前、术后临床疗效。术后2、4、6和8个月对患者进行随访，期间复查腰椎CR和CT片，测量椎间隙相对高度、Taillard指数、腰椎曲度指数、节段性和全腰椎前凸角。数据分别采用配对t检验、方差分析或LSD-t检验进行分析。
所有患者均获随访，随访时间8～13个月，平均11.32个月。术后椎间隙相对高度、Taillard指数、腰椎曲度指数、节段性和全腰椎前凸角均有显著差异，但术后不同时期差异无统计学意义。腰椎融合时间为4～8个月。
n-HA/PA66椎间融合器能恢复并维持腰椎正常稳定性，融合率高，并发症少。
