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中年患者髋部骨折后临床预后不良的预测因素。

Predictors of poor clinical outcome following hip fracture in middle aged-patients.

作者信息

Ray Robbie I, Aitken Stuart A, McQueen Margaret M, Court-Brown Charles M, Ralston Stuart H

机构信息

Department of Orthopaedics, Royal Infirmary of Edinburgh, Edinburgh, United Kingdom.

Department of Orthopaedics, Royal Infirmary of Edinburgh, Edinburgh, United Kingdom.

出版信息

Injury. 2015 Apr;46(4):709-12. doi: 10.1016/j.injury.2014.11.005. Epub 2014 Nov 15.

Abstract

The aim of this study was to investigate morbidity and mortality following hip fractures in middle aged patients. In addition, we aimed to identify risk factors which could be used to predict postoperative complications. All patients aged 40-55 who sustained a hip fracture in Lothian from 2007 to 2008 were identified from a prospective trauma database. The main outcomes were complications and 5-year mortality. Thirty hip fractures were included in the study. Complications occurred in nine (30%) cases. Deep infection was seen in three cases (10%). Mortality was 20% at 5 years, 26 times higher than for the general population. All surviving patients were contacted for risk factor analysis (24). Low energy fractures, alcohol excess, smoking and history of previous fractures were significantly associated with complications (p<0.05). Complications only occurred amongst low energy fractures. Risk factors were further analysed using the WHO FRAX algorithm. No patient with a FRAX score of less than 10 suffered a complication, whereas 50% of patients who had a FRAX score of more than 10 suffered a complication. The results of our study suggest that low energy hip fractures in middle age are due to underlying morbidity and are associated with a high incidence of postoperative complications and mortality. The FRAX score could be used as a simple method of identifying patients in this age group who are at risk of a poor outcome.

摘要

本研究的目的是调查中年患者髋部骨折后的发病率和死亡率。此外,我们旨在确定可用于预测术后并发症的风险因素。从一个前瞻性创伤数据库中识别出2007年至2008年在洛锡安发生髋部骨折的所有40 - 55岁患者。主要结局是并发症和5年死亡率。该研究纳入了30例髋部骨折患者。9例(30%)出现并发症。3例(10%)发生深部感染。5年死亡率为20%,比普通人群高26倍。对所有存活患者进行了风险因素分析(24例)。低能量骨折、过量饮酒、吸烟和既往骨折史与并发症显著相关(p<0.05)。并发症仅发生在低能量骨折患者中。使用世界卫生组织的FRAX算法对风险因素进行了进一步分析。FRAX评分低于10的患者无一发生并发症,而FRAX评分高于10的患者中有50%发生了并发症。我们的研究结果表明,中年患者的低能量髋部骨折是由潜在疾病引起的,并且与术后并发症和死亡率的高发生率相关。FRAX评分可作为一种简单的方法来识别该年龄组中预后不良风险的患者。

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