葡聚糖稳定的银纳米颗粒的一锅光辅助绿色合成、储存及抗菌活性
One pot light assisted green synthesis, storage and antimicrobial activity of dextran stabilized silver nanoparticles.
作者信息
Hussain Muhammad Ajaz, Shah Abdullah, Jantan Ibrahim, Tahir Muhammad Nawaz, Shah Muhammad Raza, Ahmed Riaz, Bukhari Syed Nasir Abbas
机构信息
Department of Chemistry, University of Sargodha, Sargodha, 40100, Pakistan.
Drug and Herbal Research Centre, Faculty of Pharmacy, Universiti Kebangsaan Malaysia, Jalan Raja Muda Abdul Aziz, Kuala Lumpur, 50300, Malaysia.
出版信息
J Nanobiotechnology. 2014 Dec 3;12:53. doi: 10.1186/s12951-014-0053-5.
BACKGROUND
Green synthesis of nanomaterials finds the edge over chemical methods due to its environmental compatibility. Herein, we report green synthesis of silver nanoparticles (Ag NPs) mediated with dextran. Dextran was used as a stabilizer and capping agent to synthesize Ag NPs using silver nitrate (AgNO3) under diffused sunlight conditions.
RESULTS
UV-vis spectra of as synthesized Ag nanoparticles showed characteristic surface plasmon band in the range from ~405-452 nm. Scanning electron microscopy (SEM) and atomic force microscopy (AFM) studies showed spherical Ag NPs in the size regime of ~50-70 nm. Face centered cubic lattice of Ag NPs was confirmed by powder X-ray diffraction (PXRD). FT-IR spectroscopy confirmed that dextran not only acts as reducing agent but also functionalizes the surfaces of Ag NPs to make very stable dispersions. Moreover, on drying, the solution of dextran stabilized Ag NPs resulted in the formation of thin films which were found stable over months with no change in the plasmon band of pristine Ag NPs. The antimicrobial assay of the as synthesized Ag NPs showed remarkable activity.
CONCLUSION
Being significantly active against microbes, the Ag NPs can be explored for antimicrobial medical devices.
背景
纳米材料的绿色合成因其环境兼容性而优于化学方法。在此，我们报告了由葡聚糖介导的银纳米颗粒（Ag NPs）的绿色合成。在漫射阳光条件下，使用硝酸银（AgNO₃），以葡聚糖作为稳定剂和封端剂来合成Ag NPs。
结果
合成的银纳米颗粒的紫外可见光谱在约405 - 452 nm范围内显示出特征表面等离子体带。扫描电子显微镜（SEM）和原子力显微镜（AFM）研究表明，Ag NPs呈球形，尺寸范围约为50 - 70 nm。粉末X射线衍射（PXRD）证实了Ag NPs的面心立方晶格。傅里叶变换红外光谱（FT - IR）证实，葡聚糖不仅作为还原剂，还使Ag NPs的表面功能化，从而形成非常稳定的分散体。此外，干燥后，葡聚糖稳定的Ag NPs溶液形成了薄膜，这些薄膜在数月内保持稳定，原始Ag NPs的等离子体带没有变化。合成的Ag NPs的抗菌试验显示出显著的活性。
结论
由于对微生物具有显著活性，Ag NPs可用于抗菌医疗设备的研发。
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