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颅内动脉瘤诊断和介入治疗中的患者辐射剂量:单中心经验。

Patient radiation dose in diagnostic and interventional procedures for intracranial aneurysms: experience at a single center.

机构信息

Department of Radiology, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul 137-701, Korea.

Department of Neurosurgery, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul 137-701, Korea.

出版信息

Korean J Radiol. 2014 Nov-Dec;15(6):844-9. doi: 10.3348/kjr.2014.15.6.844. Epub 2014 Nov 7.

Abstract

OBJECTIVE

To assess patient radiation doses during cerebral angiography and embolization of intracranial aneurysms in a large sample size from a single center.

MATERIALS AND METHODS

We studied a sample of 439 diagnostic and 149 therapeutic procedures for intracranial aneurysms in 480 patients (331 females, 149 males; median age, 57 years; range, 21-88 years), which were performed in 2012 with a biplane unit. Parameters including fluoroscopic time, dose-area product (DAP), and total angiographic image frames were obtained and analyzed.

RESULTS

Mean fluoroscopic time, total mean DAP, and total image frames were 12.6 minutes, 136.6 ± 44.8 Gy-cm(2), and 251 ± 49 frames for diagnostic procedures, 52.9 minutes, 226.0 ± 129.2 Gy-cm(2), and 241 frames for therapeutic procedures, and 52.2 minutes, 334.5 ± 184.6 Gy-cm(2), and 408 frames for when both procedures were performed during the same session. The third quartiles for diagnostic reference levels (DRLs) were 14.0, 61.1, and 66.1 minutes for fluoroscopy time, 154.2, 272.8, and 393.8 Gy-cm(2) for DAP, and 272, 276, and 535 for numbers of image frames in diagnostic, therapeutic, and both procedures in the same session, respectively. The proportions of fluoroscopy in DAP for the procedures were 11.4%, 50.5%, and 36.1%, respectively, for the three groups. The mean DAP for each 3-dimensional rotational angiographic acquisition was 19.2 ± 3.2 Gy-cm(2). On average, rotational angiography was used 1.4 ± 0.6 times/session (range, 1-4; n = 580).

CONCLUSION

Radiation dose in our study as measured by DAP, fluoroscopy time and image frames did not differ significantly from other reported DRL studies for cerebral angiography, and DAP was lower with fewer angiographic image frames for embolization. A national registry of radiation-dose data is a necessary next step to refine the dose reference level.

摘要

目的

评估单中心 480 例患者 439 例诊断性和 149 例治疗性颅内动脉瘤脑血管造影和栓塞术中的患者辐射剂量。

材料与方法

我们研究了 2012 年使用双平面设备进行的 480 例患者(331 例女性,149 例男性;中位年龄 57 岁;范围 21-88 岁)中 439 例诊断性和 149 例治疗性颅内动脉瘤的样本。获取并分析透视时间、剂量面积乘积(DAP)和总血管造影图像帧数等参数。

结果

诊断性操作的平均透视时间、总平均 DAP 和总图像帧数分别为 12.6 分钟、136.6±44.8Gy-cm(2)和 251±49 帧,治疗性操作分别为 52.9 分钟、226.0±129.2Gy-cm(2)和 241 帧,同期同时进行诊断和治疗性操作分别为 52.2 分钟、334.5±184.6Gy-cm(2)和 408 帧。诊断参考水平(DRL)的第三四分位数分别为透视时间的 14.0、61.1 和 66.1 分钟,DAP 的 154.2、272.8 和 393.8Gy-cm(2),以及诊断、治疗和同期同时进行的两种操作的图像帧数分别为 272、276 和 535。这三组中透视时间在 DAP 中的比例分别为 11.4%、50.5%和 36.1%。每个 3 维旋转血管造影采集的平均 DAP 为 19.2±3.2Gy-cm(2)。平均而言,旋转血管造影术每次/每次使用 1.4±0.6 次(范围 1-4;n=580)。

结论

我们的研究中,以 DAP、透视时间和图像帧数衡量的辐射剂量与其他报告的脑动脉造影 DRL 研究无显著差异,栓塞术的 DAP 较低,血管造影图像帧数较少。辐射剂量数据国家登记是细化剂量参考水平的必要下一步。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/60c6/4248642/47444008176b/kjr-15-844-g001.jpg

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