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孕期病假的预测因素:一项丹麦队列研究。

Predictors of sickness absence in pregnancy: a Danish cohort study.

作者信息

Hansen Mette Lausten, Thulstrup Ane Marie, Juhl Mette, Kristensen Jette Kolding, Ramlau-Hansen Cecilia Høst

机构信息

Department of Occupational Medicine, Danish Ramazzini Centre, Aarhus University Hospital, Nørrebrogade 44 building 2C, 8000 Aarhus C, Denmark. [Email:

出版信息

Scand J Work Environ Health. 2015 Mar;41(2):184-93. doi: 10.5271/sjweh.3470. Epub 2014 Dec 3.

Abstract

OBJECTIVE

The aim of this cohort study was to investigate associations between parity, pre-pregnancy body mass index (BMI), assisted reproductive therapy (ART), time to pregnancy (TTP), and engagement in physical exercise and the risk of sickness absence in pregnancy from 10-29 completed pregnancy weeks.

METHODS

Data from 51 874 pregnancies in the Danish National Birth Cohort collected from 1996 until 2002 were linked to the Danish Register for Evaluation of Marginalization. Exposure information was based on questionnaires. Hazard ratios (HR) with 95% confidence intervals (95% CI) were calculated by Cox regression, using time of first episode of sickness absence as the primary outcome.

RESULTS

Multiparity 1.26 (95% CI 1.10-1.45), overweight 1.13 (95% CI 1.08-1.18), obesity 1.23 (95% CI 1.15-1.31), ART 1.10 (95% CI 1.01-1.20), and TTP >12 months 1.06 (95% CI 0.99-1.13) were associated with higher HR of sickness absence. Physical exercise of >120 minutes per week was associated with lower HR 0.84 (95% CI 0.75-0.95).

CONCLUSION

Risk for sickness absence was higher among women who were multiparous, overweight, obese, received ART, and had prolonged TTP, and lower among women engaged in leisure-time physical exercise. Few studies have investigated these associations, and the results should be confirmed in other studies of pregnant women.

摘要

目的

本队列研究旨在调查产次、孕前体重指数(BMI)、辅助生殖技术(ART)、怀孕时间(TTP)、体育锻炼与妊娠10 - 29孕周期间病假风险之间的关联。

方法

将1996年至2002年丹麦国家出生队列中51874例妊娠的数据与丹麦边缘化评估登记处相链接。暴露信息基于问卷调查。以首次病假时间为主要结局,通过Cox回归计算风险比(HR)及95%置信区间(95%CI)。

结果

多产1.26(95%CI 1.10 - 1.45)、超重1.13(95%CI 1.08 - 1.18)、肥胖1.23(95%CI 1.15 - 1.31)、ART 1.10(95%CI 1.01 - 1.20)以及TTP>12个月1.06(95%CI 0.99 - 1.13)与病假的较高HR相关。每周体育锻炼>120分钟与较低的HR 0.84(95%CI 0.75 - 0.95)相关。

结论

多产、超重、肥胖、接受ART以及TTP延长的女性病假风险较高,而进行休闲体育锻炼的女性病假风险较低。很少有研究调查这些关联,结果应在其他孕妇研究中得到证实。

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